The role of neoadjuvant radiotherapy for locally-advanced rectal cancer with resectable synchronous metastasis

Figure 3: Overall survival: 5-year overall survival rates were: 43.3% (95% CI: 30.1, 62.3%) (no RT) vs. 58.3% (95% CI: 43.4%, 78.2%) (RT). The 5-year disease-specific survival rates were 49.6% (95% CI: 35.5%, 69.4%) (no RT) vs. 60.5% (95% CI: 45.0%, 81.33%) (RT). RT, radiotherapy.

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A margin distance analysis of the impact of adjuvant chemoradiation on survival after pancreatoduodenectomy for pancreatic adenocarcinoma

Figure 1: Kaplan-Meier estimates for (A) recurrence-free survival (RFS) and (B) overall survival (OS) for patients stratified by margin clearance (MC) following pancreaticoduodenectomy (PD)

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Novel Biologics In Era of Precision Medicine by Drs. Andrea Wang-Gillam and Kian-Huat Lim

This issue is organized into four sections: (I) Evolution In Cancer Treatment: Adding Genomics to Histology; (II) Biologics in Various GI Malignancies; (III) Challenges in Biologics; (IV) Ongoing Perspectives and Clinical Trials.  It is dedicated to providing readers with an updated and concise overview of novel biologics that are being developed or tested in various GI cancer types. Efforts toward the molecular classification for each GI cancer type will be discussed, and expert insight into the challenges of precision oncology including treatment resistance, side effects and cost-effectiveness will be presented.  

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Neoadjuvant transarterial radiation lobectomy for colorectal hepatic metastases: a small cohort analysis on safety, efficacy, and radiopathologic correlation

Contrast-enhanced CT of the abdomen in the portal venous phase demonstrating a large heterogeneously enhancing mass in the right hepatic lobe (arrow in A) in patient 1 prior to radiation lobectomy. Two months following RL, the lesion is smaller and necrotic without evidence of internal enhancement (arrow in B). Note FLR hypertrophy (star) and decreased volume of the right hepatic lobe (arrowhead).

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Optimizing the management of hepatobiliary neoplasms: a multidisciplinary and molecular challenge by Dr. Jimmy Hwang

In this issue of Journal of Gastrointestinal Oncology (JGO), a variety of comprehensive reviews highlight the multidisciplinary advancements and efforts required for optimizing care for patients with hepatobiliary neoplasms. This series, written by experts from a variety of oncologic specialties, highlights the imperative of coordinated multidisciplinary efforts both in the clinic and, most importantly, in future research endeavors that incorporate the growing body of molecular, technical, and pharmacologic advances.

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2016 Annual Report of JGO

We are glad to present the 2016 Annual Report of JGO here. In 2016, JGO was indexed in Scopus. The total citation number significantly increased to 1,761 in 2016. And the retrieval of the journal in PubMed was impressive, with a total of 455,020 times. More information is shown in the Annual Report.

We give our sincere thanks to all our editorial board members, reviewers, authors and readers. We wish you a happy, healthy and productive 2017!

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A Marriage between AME Publishing Company and The World Society Of Emergency Surgery in academic cooperation

We are glad to announce that the World Society Of Emergency Surgery has entered into a strategic cooperation agreement with AME Publishing Company on Friday, February 24, 2017.

This cooperation could be regarded as a combination of the resource advantage of AME and WSES. According to Dr. Federico Coccolini, an active member of the board of WSES, WSES has been publishing guidelines since almost ten years, leading some of the main emergency and trauma surgery fields. 

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Results of intraoperative electron beam radiotherapy containing multimodality treatment for locally unresectable T4 rectal cancer: a pooled analysis of the Mayo Clinic Rochester and Catharina Hospital Eindhoven

Influence of waiting time (interval from end of preoperative therapy to surgery).

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Clinical, morphologic, and immunophenotypic characteristics of ampullary carcinomas with an emphasis on SMAD4 expression

SMAD4 immunohistochemical studies (IHC) expression patterns in ampullary adenocarcinoma. (A) Diffuse (strong staining comparable to surrounding pancreas); (B) focal (two cell population with a subset of clearly negative cells) (100×); (C) trace (weak reactivity relative to surrounding pancreas); (D) absent (no staining). (A, C, D: 200×).

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