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Original Article

Immune profiling of microsatellite instability-high and polymerase ε (POLE)-mutated metastatic colorectal tumors identifies predictors of response to anti-PD-1 therapy
Chongkai Wang, Jun Gong, Travis Y. Tu, Peter P. Lee, Marwan Fakih
Germline pharmacogenomics of DPYD*9A (c.85T>C) variant in patients with gastrointestinal malignancies treated with fluoropyrimidines
Moh’d Khushman, Girijesh Kumar Patel, Peter Joel Hosein, Javier Ariel Laurini, Daniel Cameron, David Roland Clarkson, Thomas Wayne Butler, Carole Wiseman Norden, Wilma Baliem, Vanessa Jones, Sanjyot Bhadkamkar, Cindy Nelson, Frances Lee, Ajay P. Singh, William R. Taylor
Cost-utility analysis of 5-fluorouracil and capecitabine for adjuvant treatment in locally advanced rectal cancer
Kanyarat Katanyoo, Imjai Chitapanarux, Tharatorn Tungkasamit, Somvilai Chakrabandhu, Marisa Chongthanakorn, Rungarun Jiratrachu, Apiradee Kridakara, Kanokpis Townamchai, Pooriwat Muangwong, Chokaew Tovanabutra, Kittisak Chomprasert
Preferential use of imaging modalities in staging newly diagnosed rectal cancer: a survey of US radiation oncologists
Jehan Belal Yahya, Matthew Joseph Farrell, Daniel O. Herzig, Catherine R. Degnin, Yiyi Chen, John Holland, Simon Brown, Jerry Jaboin, Charles R. Thomas Jr, Timur Mitin
Does a fine line exist between regional and metastatic pelvic lymph nodes in rectal cancer—striking discordance between national guidelines and treatment recommendations by US radiation oncologists
Jehan Belal Yahya, Daniel O. Herzig, Matthew Joseph Farrell, Catherine R. Degnin, Yiyi Chen, John Holland, Simon Brown, Jerry Jaboin, Vassiliki Liana Tsikitis, Kim Lu, Charles R. Thomas Jr, Timur Mitin
Single nucleotide polymorphism rs4648298 in miRNAs hsa-miR21 and hsa-miR590 binding site of COX gene is a strong colorectal cancer determinant
Meysam Mosallaei, Miganoosh Simonian, Fateme Ahangari, Maryam Miraghajani, Deniz Mortazavi, Ahmad Reza Salehi, Sharifeh Khosravi, Rasoul Salehi
Demographic characteristics and the first program of colorectal cancer (CRC) screening in north of Iran (2016)
Hossein-Ali Nikbakht, Haleh Ghaem, Javad Shokri-Shirvani, Saber Ghaffari-fam, Sedigheh Alijanpour
Utilization of intensity modulated radiation therapy for anal cancer in the United States
Waqar Haque, Vivek Verma, E. Brian Butler, Bin S. Teh
The platelets-neutrophils to lymphocytes ratio: a new prognostic marker in metastatic colorectal cancer
Joey Mercier, Ioannis A. Voutsadakis
Adjuvant radiation provides survival benefit for resected pancreatic adenocarcinomas of the tail
William H. Jin, Sarah E. Hoffe, Ravi Shridhar, Tobin Strom, Puja Venkat, Gregory M. Springett, Pamela J. Hodul, Jose M. Pimiento, Kenneth L. Meredith, Mokenge P. Malafa, Jessica M. Frakes
Palliative care and end-of-life health care utilization in elderly patients with pancreatic cancer
Nizar Bhulani, Arjun Gupta, Ang Gao, Jenny Li, Chad Guenther, Chul Ahn, Elizabeth Paulk, Stephanie Houck, Muhammad S. Beg
Disparities in major surgery for esophagogastric cancer among hospitals by case volume
Emmanuel Gabriel, Sumana Narayanan, Kristopher Attwood, Steven Hochwald, Moshim Kukar, Steven Nurkin
Clinical impact of underutilization of adjuvant therapy in node positive gastric adenocarcinoma
Rebecca Zhu, Fangfang Liu, Gabriella Grisotti, Javier Perez-Irizarry, Ronald R. Salem, Charles H. Cha, Kimberly L. Johung, Daniel J. Boffa, Yawei Zhang, Sajid A. Khan
Chemoradiotherapy versus chemotherapy alone for unresected intrahepatic cholangiocarcinoma: practice patterns and outcomes from the national cancer data base
Vivek Verma, Adams Kusi Appiah, Tim Lautenschlaeger, Sebastian Adeberg, Charles B. Simone II, Chi Lin
Non-surgical management of patients with intrahepatic cholangiocarcinoma in the United States, 2004–2015: an NCDB analysis
Andrew R. Kolarich, Jehan L. Shah, Thomas J. George Jr, Steven J. Hughes, Christiana M. Shaw, Brian S. Geller, Joseph R. Grajo
Viral hepatitis associated hepatocellular carcinoma outcomes with yttrium-90 radioembolization
Jessica M. Frakes, Yazan A. Abuodeh, Arash O. Naghavi, Michelle I. Echevarria, Ravi Shridhar, Mark Friedman, Richard Kim, Ghassan El-Haddad, Bela Kis, Benjamin Biebel, Jennifer Sweeney, Junsung Choi, Daniel Anaya, Anna R. Giuliano, Sarah E. Hoffe

Short Communication

Aggressive mutation in a familial adenomatous polyposis syndrome family: when phenotype guides clinical surveillance
Florencia Neffa, Lucia Garcia, Adriana Della Valle, Florencia Carusso, Carolina Vergara, Daniel Sanchez, Marta Sapone, Noelia Silveyra, Ana Laura Revello, Patricia Esperon

Case Report

Oxaliplatin-induced bronchiolitis obliterans organizing pneumonia following hyperthermic intraperitoneal chemotherapy
Guillaume Le Baut, Jean-Marc Guilloit, Vincent Leprince, Yann Ollivier, Catherine Dubos-Arvis, Pascal Do, Jasmine Sutter, Ludovic Loge, Radj Gervais

Original Article

Survival of metastatic gastric cancer: Significance of age, sex and race/ethnicity
Dongyun Yang, Andrew Hendifar, Cosima Lenz, Kayo Togawa, Felicitas Lenz, Georg Lurje, Alexandra Pohl, Thomas Winder, Yan Ning, Susan Groshen, Heinz-Josef Lenz
The clinical utility of serum CA 19-9 in the diagnosis, prognosis and management of pancreatic adenocarcinoma: An evidence based appraisal
Umashankar K Ballehaninna, Ronald S Chamberlain

Review Article

Colorectal carcinoma: Pathologic aspects
Matthew Fleming, Sreelakshmi Ravula, Sergei F. Tatishchev, Hanlin L. Wang
HDR brachytherapy for anal cancer
Peter Niehoff, Gyoergy Kovács
Gastric cancer: Classification, histology and application of molecular pathology
Bing Hu, Nassim El Hajj, Scott Sittler, Nancy Lammert, Robert Barnes, Aurelia Meloni-Ehrig
Techniques of hepatic resection
Robert J. Aragon, Naveenraj L. Solomon
Immunohistochemical features of the gastrointestinal tract tumors
Hannah H. Wong, Peiguo Chu

Review Article

Imaging of pancreatic cancer: An overview
Pavan Tummala, Omer Junaidi, Banke Agarwal

Original Article

Bax expression is a candidate prognostic and predictive marker of colorectal cancer
Venkat R Katkoori, Catalina Suarez-Cuervo, Chandrakumar Shanmugam, Nirag C Jhala, Tom Callens, Ludwine Messiaen, James Posey III, Harvey L Bumpers, Sreelatha Meleth, William E Grizzle, Upender Manne
Survival of metastatic gastric cancer: Significance of age, sex and race/ethnicity
Dongyun Yang, Andrew Hendifar, Cosima Lenz, Kayo Togawa, Felicitas Lenz, Georg Lurje, Alexandra Pohl, Thomas Winder, Yan Ning, Susan Groshen, Heinz-Josef Lenz
The influence of radiation therapy dose escalation on overall survival in unresectable pancreatic adenocarcinoma
William A. Hall, Lauren E. Colbert, Dana Nickleach, Jeffrey Switchenko, Yuan Liu, Theresa Gillespie, Joseph Lipscomb, Claire Hardy, David A. Kooby, Roshan S. Prabhu, John Kauh, Jerome C. Landry
Overall survival analysis of neoadjuvant chemoradiotherapy and esophagectomy for esophageal cancer
Faisal A. Siddiqui, Katelyn M. Atkins, Brian S. Diggs, Charles R. Thomas Jr, John G. Hunter, James P. Dolan
Radiotherapy patterns of care in gastric adenocarcinoma: a single institution experience
Jessica Cheng, Malcolm H. Squires III, John L. Mikell, Sarah B. Fisher, Charles A. Staley III, David A. Kooby, Bassel F. El-Rayes, Walter J. Curran Jr, William A. Hall, Lauren E. Colbert, Joseph W. Shelton, Shishir K. Maithel, Jerome Landry, David S. Yu

Review Article

Alcoholic liver disease- Hepatocellular carcinoma transformation
Samuel W French, James Lee, Jim Zhong, Timothy R Morgan, Virgil Buslon, William Lungo, Barbara A French
Pancreatic adenocarcinoma pathology: changing “landscape”
Lodewijk A. A. Brosens, Wenzel M. Hackeng, G. Johan Offerhaus, Ralph H. Hruban, Laura D. Wood

Original Articles

Socioeconomic status, p53 abnormalities, and colorectal cancer
Emily Vogtmann, Chandrakumar Shanmugam, Venkat R. Katkoori, John Waterbor, Upender Manne
Nab-paclitaxel monotherapy in refractory pancreatic adenocarcinoma
Parvin F. Peddi, May Cho, Jian Wang, Feng Gao, Andrea Wang-Gillam

Below are the latest Journal of Gastrointestinal Oncology articles published online ahead of print publication.

Original Article


Review Article


Case Report