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Original Article

Magnetic resonance elastography can predict the development of hepatocellular carcinoma: a meta-analysis and systematic review
Lianglong Wu, Junying Bi, Liangjin Liu, Yanni Zeng
Clinical value of lymph node dissection for stage T1b mid-thoracic esophageal squamous cell carcinoma
Xiaofeng Chen, Yujie Chen, Feng Wang, Shuoyan Liu, Peng Chen, Hao He
Evaluating prognostic value and relevant gene signatures of tumor microenvironment characterization in esophageal carcinoma
Wang Sheng, Xiaoyu Li, Jiayi Li, Yanjun Mi, Fan Li
Construction and evaluation of prognostic models for esophageal cancer patients with distant and non-distant metastases: providing a reference process for clinical diagnosis and treatment
Mingxin Zhang, Manli Cui, Qianqian Zuo, Li Wang, Jia Wang, Lin Zhu, Rong Yan, Ning Lu, Honglin Yan, Lingmin Zhang
Effectiveness of telerehabilitation on short-term quality of life of patients after esophageal cancer surgery during COVID-19: a single-center, randomized, controlled study
Keqing Chen, Fei Yao, Xiaoyu Chen, Yanjuan Lin, Minqiang Kang
The relationship between the number of circulating tumor cells and the prognosis in patients with esophageal squamous cell carcinoma
Zhipeng Ren, Xiaobin Hou, Zhiqiang Xue, Lianbin Zhang, Bo Wang, Jiaxin Wen, Xiangyang Chu
Comparative study on short-term efficacy of single incision plus one (SI+1) port and multiportal 3D laparoscopic minimally invasive esophagectomy
Ning Xin, Rongqiang Wei, Kenan Huang, Zihao Chen, Chengdong Liu, Yunhao Fang, Zhifei Xu, Xinyu Ding, Hua Tang
Prognostic performance of different lymph node classification systems in young gastric cancer
Yi-Ru Chen, Mei-Qian Wang, Yi-Ting Li, Ping Li, Su-Shan Ouyang, Hui-Wen Xu, Sen-Lin Zhu
Clinicopathologic differences and mortality among Latinos and non-Latino whites with gastric cancer at a majority-minority cancer center in South Texas
Madison H. Williams, Ryan A. Williams, Brian Hernandez, Joel Michalek, Dorothy Long Parma, Sukeshi P. Arora
Disparities and survival in newly diagnosed gastric cancer in Hispanic patients in the United States: a propensity score matched analysis
Joshua Tseng, James P. Miller, Jeffrey Johnson, Kevin Waters, Alexandra Gangi, Jun Gong, Miguel Burch
Slug and CD133 expression are associated with peritoneal carcinomatosis and survival in gastric cancer
Joori Kim, Kabsoo Shin, Sung Hak Lee, In-Ho Kim
Decreased albumin-to-alkaline phosphatase ratio predicted poor survival of resectable gastric cancer patients
Yan Wang, Feng Xiong, Jian Yang, Tingting Xia, Zhenyu Jia, Jiaqing Shen, Chunfang Xu, Jun Feng, Yongda Lu
Value of multiphase contrast-enhanced CT with three-dimensional reconstruction in detecting depth of infiltration, lymph node metastasis, and extramural vascular invasion of gastric cancer
Junda Wang, Lijuan Zhong, Xinjie Zhou, Demei Chen, Rui Li
AKT inhibits the phosphorylation level of H2A at Tyr57 via CK2α to promote the progression of gastric cancer
Zhi-Da Chen, Peng-Fei Zhang, Hong-Qing Xi, Bo Wei, Lin Chen
Diagnostic and prognostic value of MATN3 expression in gastric carcinoma: TCGA database mining
Ding Li, Jianqiu Xu, Xiaochen Dong, Wenjing Chen, Lingling Pan, Hao Jiang, Jingye Pan, Yueyue Huang
Differential analysis of RNA methylation regulators in gastric cancer based on TCGA data set and construction of a prognostic model
Jing Li, Zhifan Zuo, Shusheng Lai, Zhendong Zheng, Bo Liu, Yuan Wei, Tao Han
Predictive values profiling of interleukin-2, interleukin-8, tumor necrosis factor-α, procalcitonin, and C-reactive protein in critical gastrointestinal cancer patients
Yamin Yan, Zhenghong Yu, Jingjing Lu, Peili Jin, Zhaoqing Tang, Yan Hu
Anatomical observation and clinical significance of the left gastric vein in laparoscopic radical gastrectomy
Xiaofeng Zhu, Qiang Zhao, Wenjun Xiong, Lijie Luo, Yansheng Zheng, Haipeng Huang, Jin Li, Jin Wan, Wei Xie, Wei Wang
Neoadjuvant intraperitoneal and systemic paclitaxel combined with apatinib and S-1 chemotherapy for conversion therapy in gastric cancer patients with positive exfoliative cytology: a prospective study
Ping’an Ding, Peigang Yang, Yuan Tian, Honghai Guo, Yang Liu, Ze Zhang, Tao Zheng, Bibo Tan, Zhidong Zhang, Dong Wang, Yong Li, Qun Zhao
Candidate oncogene circularNOP10 mediates gastric cancer progression by regulating miR-204/SIRT1 pathway
Jiajia Xu, Xueqing Wang, Weijie Wang, Lihua Zhang, Peilin Huang
Lymph node metastasis risk factors and applicability of endoscopic submucosal dissection in mixed-type early gastric cancer in Chinese patients
Pengwei Liu, Lin Li, Jing Wang, Hong Song, Chiyi He
Microwave ablation for colorectal cancer metastasis to the liver: a single-center retrospective analysis
Emily A. Knott, Timothy J. Ziemlewicz, Sam J. Lubner, John F. Swietlik, Sharon M. Weber, Annie M. Zlevor, Colin Longhurst, J. Louis Hinshaw, Meghan G. Lubner, Daniel L. Mulkerin, Daniel E. Abbott, Dustin Deming, Noelle K. LoConte, Nataliya Uboha, Allison B. Couillard, Shane A. Wells, Paul F. Laeseke, Marci L. Alexander, Fred T. Lee Jr
Prognostic value of the ratio of carcinoembryonic antigen concentration to maximum tumor diameter in patients with stage II colorectal cancer
Xianzhe Li, Zhizhong Xiong, Minghao Xie, Qunsheng Huang, Longyang Jin, Shi Yin, Shuanggang Chen, Ping Lan, Lei Lian
Factors associated with the refusal of surgery and the associated impact on survival in patients with rectal cancer using the National Cancer Database
Alex R. Coffman, Randa Tao, Jessica N. Cohan, Lyen C. Huang, T. Bartley Pickron, Anna M. Torgeson, Shane Lloyd
Development of a model to predict pathologic response to chemotherapy in patients with colorectal liver metastases
Da Xu, Yan-Yan Wang, Xiao-Luan Yan, Juan Li, Kun Wang, Bao-Cai Xing
Influence of first line chemotherapy strategy depending on primary tumor location in metastatic colorectal cancer
Zoé Tharin, Julie Blanc, Ikram Charifi Alaoui, Aurélie Bertaut, Francois Ghiringhelli
Risk of delayed bleeding after hot snare polypectomy and endoscopic mucosal resection in the colorectum with continuation of anticoagulants
Takamasa Kobayashi, Manabu Takeuchi, Yuki Hojo, Yui Ishii, Youhei Koseki, Yoko Kobayashi, Motoi Azumi, Yuji Kobayashi, Junji Kohisa, Seiichi Yoshikawa, Shuji Terai
The efficacy and safety of different radiotherapy doses in neoadjuvant chemoradiotherapy for locally advanced rectal cancer
Yongchun Zhang, Peng Jiang, Hui Zhu, Bin Dong, Hanxiao Zhai, Zhiying Chen
The predictive value of RNA binding proteins in colon adenocarcinoma
Lipeng Luan, Feng Lu, Xiaochuan Wang, Yunliang Wang, Wei Wang, Yong Yang, Guoliang Chen, Huihui Yao, Xinyu Shi, Zihan Yuan, Guoqiang Zhou, Haitao Zhang, Songbing He
Optimal adjuvant chemotherapy completion time for stage III colon cancer: a cohort study
Jing-Qing Ren, Han-Shuo Zhang, Li-Hua Zhang, Qi-Guang Zhong, Fan Wu, Bai-Lin Wang, Shao-Jie Liu
Outcomes of colorectal cancer surgery in nonagenarian patients: a multicenter retrospective study
Wei-Gen Zeng, Meng-Jia Liu, Zhi-Xiang Zhou, Jun-Jie Hu, Zhen-Jun Wang
Expression, clinical significance and correlation of RUNX3 and HER2 in colorectal cancer
Yunshi Wu, Jun Xue, Yuanrui Li, Xueliang Wu, Ming Qu, Dandan Xu, Yongquan Shi
A methylation-based prognostic model predicts survival in patients with colorectal cancer
Shanyue Tan, Weiwei Gui, Sumeng Wang, Chongqi Sun, Xian Xu, Lingxiang Liu
Effects of YAP1 and SFRP2 overexpression on the biological behavior of colorectal cancer cells and their molecular mechanisms
Zhenzhen Bai, Qingqing Wu, Cong Zhang, Jing Chen, Liyu Cao
Identification of hub genes and functional modules in colon adenocarcinoma based on public databases by bioinformatics analysis
Zhipeng Zhang, Aihong Luo, Zhijun Zeng, Yikai Zhou, Wei Wu
A dual-targeted molecular therapy of PP242 and cetuximab plays an anti-tumor effect through EGFR downstream signaling pathways in colorectal cancer
Linghui Kong, Qun Zhang, Jialei Mao, Lei Cheng, Xiao Shi, Lixia Yu, Jing Hu, Mi Yang, Li Li, Baorui Liu, Xiaoping Qian
Comparative analysis of clinical, treatment, and survival characteristics of signet ring cell and adenocarcinoma of esophagus
Zhang Peng, Feng Li, Zeng Cheng, Wu Kai, Zhao Song
Preoperative serum fibrinogen as a valuable predictor in the nomogram predicting overall survival of postoperative patients with gallbladder cancer
Ziyi Yang, Tai Ren, Shilei Liu, Chen Cai, Wei Gong, Yijun Shu
Integrative analysis of TNFRSF6B as a potential therapeutic target for pancreatic cancer
Chen Zhang, Haoran Li, Yujie Huang, Yuchen Tang, Jie Wang, Yinxiang Cheng, Yijun Wei, Dongming Zhu, Zhifei Cao, Jian Zhou
Hypoxia promotes pancreatic cancer cell migration, invasion, and epithelial-mesenchymal transition via modulating the FOXO3a/ DUSP6/ERK axis
Hua Zhao, Wei Chen, Yi Zhu, Jianying Lou
The expression and prognostic value of REXO4 in hepatocellular carcinoma
Weipeng Chen, Cheng Gao, Jianbo Shen, Lanqing Yao, Xiaoliang Liang, Zhong Chen
Prognostic factors of unresectable hepatocellular carcinoma treated with yttrium-90 radioembolization: results from a large cohort over 13 years at a single center
Rucha M. Shah, Sarah Sheikh, Jimmy Shah, Elaina Vivian, Alejandro Mejia, Islam Shahin, Parvez S. Mantry
Synergistic effects of arsenic trioxide combined with Salmonella typhimurium in treating the advanced hepatocellular carcinoma in rat models
Qing Zhao, Ying Wang, Wen-Tao Li
Ablative radiation therapy for hepatocellular carcinoma is associated with reduced treatment- and tumor-related liver failure and improved survival
Lara Hilal, Marsha Reyngold, Abraham J. Wu, Abdallah Araji, Ghassan K. Abou-Alfa, William Jarnagin, James J. Harding, Maya Gambarin, Imane El Dika, Paul Brady, John Navilio, Sean L. Berry, Jessica Flynn, Zhigang Zhang, Richard Tuli, Melissa Zinovoy, Paul B. Romesser, John J. Cuaron, Christopher H. Crane, Carla Hajj
Proton stereotactic body radiation therapy for liver metastases—results of 5-year experience for 81 hepatic lesions
Alex R. Coffman, Daniel C. Sufficool, Joseph I. Kang, Chung-Tsen Hsueh, Sasha Swenson, Patrick Q. McGee, Gayathri Nagaraj, Baldev Patyal, Mark E. Reeves, Jerry D. Slater, Gary Y. Yang
Morphine promotes angiogenesis by activating PI3K/Akt/HIF-1α pathway and upregulating VEGF in hepatocellular carcinoma
Zhiyao Wang, Linghui Jiang, Jie Wang, Zongtao Chai, Wanxia Xiong
Bioinformatical identification of key genes regulated by IGF2BP2- mediated RNA N6-methyladenosine and prediction of prognosis in hepatocellular carcinoma
Qiang Wei
The effect of the TP53 and RB1 mutations on the survival of hepatocellular carcinoma patients with different racial backgrounds
Xiaohui Duan, Yi Cai, Tingting He, Xiaoliang Shi, Juan Zhao, Hui Zhang, Yao Shen, Hongjian Zhang, Heng Zhang, Wenbin Duan, Bo Jiang, Xianhai Mao
XPA serves as an autophagy and apoptosis inducer by suppressing hepatocellular carcinoma in a PI3K/Akt/mTOR dependent manner
Yi Deng, Qing-Song Chen, Wei-Feng Huang, Jiang-Wen Dai, Zhong-Jun Wu
miR-744-5p suppresses tumor proliferation and metastasis by targeting transforming growth factor-beta 1 (TGF-β1) in hepatocellular carcinoma (HCC)
Weifeng Huang, Qingsong Chen, Jiangweng Dai, Yuke Zhang, Yan Yi, Xufu Wei, Zhongjun Wu
FAT10 promotes hepatocellular carcinoma (HCC) carcinogenesis by mediating P53 degradation and acts as a prognostic indicator of HCC
Yue Zhang, Zhifan Zuo, Bo Liu, Pinghua Yang, Jun Wu, Lei Han, Tao Han, Tingsong Chen
Comparison of initial tumor responses to transarterial bland embolization and drug-eluting beads-transarterial chemoembolization in the management of hepatocellular carcinoma: a propensity-score matching analysis
Jianxi Guo, Weidong Wang, Yanfang Zhang, Linfeng Xu, Jian Kong
Urokinase plasminogen activator predicts poor prognosis in hepatocellular carcinoma
Fei-Yu Niu, Chuan Jin, Lei Ma, Yan-Xia Shi, Xiao-Shan Li, Peng Jiang, Sha Gao, Jin-Rong Lin, Ye Song
N6-methyladenosine (m6A) regulatory gene divides hepatocellular carcinoma into three subtypes
Jie Wei, Da Lang Fang, Weijie Zhou, Yong Fei He
MD2 blockage prevents the migration and invasion of hepatocellular carcinoma cells via inhibition of the EGFR signaling pathway
Yajun Qi, Qilu Fang, Qinglin Li, Haiying Ding, Qi Shu, Yan Hu, Wenxiu Xin, Luo Fang
Risk characteristics with seven epithelial-mesenchymal transition-related genes are used to predict the prognosis of patients with hepatocellular carcinoma
Xianqing Shi, Shuhuan Tu, Liqun Zhu
Underlying mechanism of sorafenib resistance in hepatocellular carcinoma: a bioinformatics study based on validated resistance-related genes
Yu Song, Peng Gao, Haiying Ding, Gaoqi Xu, Yan Hu, Yinghui Tong, Wenxiu Xin, Liwen Zhang, Miaolian Wu, Luo Fang
Increased RBM12 expression predicts poor prognosis in hepatocellular carcinoma based on bioinformatics
Cheng Gao, Jianbo Shen, Weipeng Chen, Lanqing Yao, Xiaoliang Liang, Renfei Zhu, Zhong Chen
Screening potential prognostic biomarkers for portal vein emboli in patients with hepatocellular carcinoma
Weijie Zhou, Da Lang Fang, Yongfei He

Review Article

Imaging of pancreatic cancer: An overview
Pavan Tummala, Omer Junaidi, Banke Agarwal
Immunohistochemical features of the gastrointestinal tract tumors
Hannah H. Wong, Peiguo Chu
Techniques of hepatic resection
Robert J. Aragon, Naveenraj L. Solomon
Gastric cancer: Classification, histology and application of molecular pathology
Bing Hu, Nassim El Hajj, Scott Sittler, Nancy Lammert, Robert Barnes, Aurelia Meloni-Ehrig
HDR brachytherapy for anal cancer
Peter Niehoff, Gyoergy Kovács
Colorectal carcinoma: Pathologic aspects
Matthew Fleming, Sreelakshmi Ravula, Sergei F. Tatishchev, Hanlin L. Wang

Original Article

The clinical utility of serum CA 19-9 in the diagnosis, prognosis and management of pancreatic adenocarcinoma: An evidence based appraisal
Umashankar K Ballehaninna, Ronald S Chamberlain
Survival of metastatic gastric cancer: Significance of age, sex and race/ethnicity
Dongyun Yang, Andrew Hendifar, Cosima Lenz, Kayo Togawa, Felicitas Lenz, Georg Lurje, Alexandra Pohl, Thomas Winder, Yan Ning, Susan Groshen, Heinz-Josef Lenz

Review Article

Alcoholic liver disease- Hepatocellular carcinoma transformation
Samuel W French, James Lee, Jim Zhong, Timothy R Morgan, Virgil Buslon, William Lungo, Barbara A French
Pancreatic adenocarcinoma pathology: changing “landscape”
Lodewijk A. A. Brosens, Wenzel M. Hackeng, G. Johan Offerhaus, Ralph H. Hruban, Laura D. Wood
Refining the management of resectable esophagogastric cancer: FLOT4, CRITICS, OE05, MAGIC-B and the promise of molecular classification
Jeremy Chuang, Jun Gong, Samuel J. Klempner, Yanghee Woo, Joseph Chao

Original Article

Bax expression is a candidate prognostic and predictive marker of colorectal cancer
Venkat R Katkoori, Catalina Suarez-Cuervo, Chandrakumar Shanmugam, Nirag C Jhala, Tom Callens, Ludwine Messiaen, James Posey III, Harvey L Bumpers, Sreelatha Meleth, William E Grizzle, Upender Manne
Survival of metastatic gastric cancer: Significance of age, sex and race/ethnicity
Dongyun Yang, Andrew Hendifar, Cosima Lenz, Kayo Togawa, Felicitas Lenz, Georg Lurje, Alexandra Pohl, Thomas Winder, Yan Ning, Susan Groshen, Heinz-Josef Lenz
The influence of radiation therapy dose escalation on overall survival in unresectable pancreatic adenocarcinoma
William A. Hall, Lauren E. Colbert, Dana Nickleach, Jeffrey Switchenko, Yuan Liu, Theresa Gillespie, Joseph Lipscomb, Claire Hardy, David A. Kooby, Roshan S. Prabhu, John Kauh, Jerome C. Landry
Overall survival analysis of neoadjuvant chemoradiotherapy and esophagectomy for esophageal cancer
Faisal A. Siddiqui, Katelyn M. Atkins, Brian S. Diggs, Charles R. Thomas Jr, John G. Hunter, James P. Dolan
Radiotherapy patterns of care in gastric adenocarcinoma: a single institution experience
Jessica Cheng, Malcolm H. Squires III, John L. Mikell, Sarah B. Fisher, Charles A. Staley III, David A. Kooby, Bassel F. El-Rayes, Walter J. Curran Jr, William A. Hall, Lauren E. Colbert, Joseph W. Shelton, Shishir K. Maithel, Jerome Landry, David S. Yu
Impact of intensity modulated radiation therapy on survival in anal cancer
Jaymin Jhaveri, Lael Rayfield, Yuan Liu, Mudit Chowdhary, Sibo Tian, Richard J. Cassidy, Theresa Gillespie, Pretesh R. Patel, Jerome C. Landry, Kirtesh R. Patel
Immune profiling of microsatellite instability-high and polymerase ε (POLE)-mutated metastatic colorectal tumors identifies predictors of response to anti-PD-1 therapy
Chongkai Wang, Jun Gong, Travis Y. Tu, Peter P. Lee, Marwan Fakih
Palliative care and end-of-life health care utilization in elderly patients with pancreatic cancer
Nizar Bhulani, Arjun Gupta, Ang Gao, Jenny Li, Chad Guenther, Chul Ahn, Elizabeth Paulk, Stephanie Houck, Muhammad S. Beg
Distinctive features of gastrointestinal stromal tumors arising from the colon and rectum
Rebecca Zhu, Fangfang Liu, Gabriella Grisotti, Javier Pérez-Irizarry, Charles H. Cha, Caroline H. Johnson, Daniel J. Boffa, Dale Han, Kimberly L. Johung, Yawei Zhang, Sajid A. Khan

Original Articles

Socioeconomic status, p53 abnormalities, and colorectal cancer
Emily Vogtmann, Chandrakumar Shanmugam, Venkat R. Katkoori, John Waterbor, Upender Manne
Nab-paclitaxel monotherapy in refractory pancreatic adenocarcinoma
Parvin F. Peddi, May Cho, Jian Wang, Feng Gao, Andrea Wang-Gillam

Below are the latest Journal of Gastrointestinal Oncology articles published online ahead of print publication.

Review Article


Original Article

Intact SMAD-4 is a predictor of increased locoregional recurrence in upfront resected pancreas cancer receiving adjuvant therapy
Hunter C. Gits, Amy H. Tang, William S. Harmsen, William R. Bamlet, Rondell P. Graham, Gloria M. Petersen, Thomas C. Smyrk, Amit Mahipal, Roman O. Kowalchuk, Jonathan B. Ashman, William G. Rule, Dawn Owen, Michelle A. Neben Wittich, Robert R. McWilliams, Thorvardur Halfdanarson, Wen Wee Ma, Terence T. Sio, Sean P. Cleary, Mark J. Truty, Michael G. Haddock, Christopher L. Hallemeier, Kenneth W. Merrell