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JGO Annual Report (2020)

Greetings from the editorial office of Journal of Gastrointestinal Oncology (JGO).

We are glad to present the 2020 Annual Report of JGO here. which has shown the number and internationality, citation and pageviews of JGO publication. In 2020, JGO obtained its first Impact Factor: 2.536. We here would like to extend our sincere gratitude to our editorial board members, guest editors, reviewers, authors and readers. We wish you a happy, healthy and prosperous 2021! We look forward to working with you in the new year to continue the success of JGO.

Global GI Malignancies

The increasing issues of globalization and caring for our populations have created a unified effort of all healthcare stakeholders worldwide. Population health has emerged to integrate public health, health policy, quality and safety, as well as chronic care management under one roof. Although the concept of population health has been around for generations, a measurable definition of “population-level health outcomes” with the health factors and policy/interventions that influence it was not reported until Kindig and Stoddart in 2003. This focus series of global GI malignancies from a population health management perspective is intended to provide a broad overview of relevant topics.

Current Strategies in Colon Cancer Management

Colorectal cancer is the second most common cancer in females and the third most common in males worldwide. In this issue of Journal of Gastrointestinal Oncology, we will focus on the surgical management of colon cancer and give an update on its latest developments.

New Impact Factor for Journal of Gastrointestinal Oncology: 2.536

We are pleased to announce that the Journal of Gastrointestinal Oncology (JGO) has attained its first impact factor update for the 2019 citation year: 2.536.

We strive to follow the best practices in publishing. The announcement of the journal’s first impact factor is not only a significant achievement for the journal but also the recognition of its more significant scientific reach. Here, we would like to extend our heartfelt gratitude to all our Editorial Team Members, Guest Editors, authors, and reviewers for their significant contributions. Read More>>

Pancreatic Neuroendocrine Tumors

The incidence of pancreatic neuroendocrine tumors (pNETs) continues to increase, prompting renewed interest in the pathophysiology and treatment of this disease. This focused series comprehensively reviews the pathophysiology, tumorigenesis, available clinical trials, and approved therapies for patients with pNETs. A deeper understanding of these factors is necessary to enhance our efforts to improve patient improve patient outcomes through the application of more innovative treatment sequencing.

Implementation of transparent peer review at Journal of Gastrointestinal Oncology (JGO)

Editorial office, Journal of Gastrointestinal Oncology

With a commitment to openness and accountability, and to increase the level of transparency throughout our peer review process, our editorial office has decided to implement a transparent peer review process as an option for all manuscripts submitted to JGO from June 11, 2020.

AME entered an official partnership with Publons to enhance wide-ranging recognition for reviewers

AME Publishing Company entered an official partnership with Publons, a product of Clarivate Analytic Company (which owns Web of Science, EndNote, ScholarOne, among many others), as of April 2020. Around 60 AME journals’ peer review systems are now integrated seamlessly into the Publons platform (https://publons.com/about/home). The partnership was done to recognize our expert peer reviewers spontaneously for their review contribution.

Congratulations to Editorial Board Members of Journal of Gastrointestinal Oncology

We are very pleased to announce that Dr. Laura Dawson, Dr. Lisa Kachnic and Dr. William Cance, who are editorial board members of Journal of Gastrointestinal Oncology, have been elected to the new leadership positions at prestigious organizations.

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Vol 11, No 6 (December, 2020)

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Original Article

Genomic characteristics in neoadjuvant chemoradiotherapy for locally advanced esophageal squamous cell carcinoma

Wenwu He, Xuefeng Leng, Kangning Wang, Tiaoqin Mao, Lin Peng, Qiang Fang, Wenguang Xiao, Yongtao Han

PDF Pages: 1105-1112 Full Text Reporting Checklist Data Sharing Statement COI Form Open Access

miR-125b prevent the progression of esophageal squamous cell carcinoma through the p38-MAPK signaling pathway

Chun Cheng, Qinghua Mao, Minxin Shi, Haimin Lu, Biao Shen, Ting Xiao, Aimin Yang, Yupeng Liu

PDF Pages: 1113-1122 Full Text Reporting Checklist Data Sharing Statement COI Form Open Access

Qingjie Fuzheng Granules regulates cancer cell proliferation, apoptosis and tumor angiogenesis in colorectal cancer xenograft mice via Sonic Hedgehog pathway

Xiao-Qin Zhu, Hong Yang, Ming-He Lin, Hai-Xia Shang, Jun Peng, Wu-Jin Chen, Xu-Zheng Chen, Jiu-Mao Lin

PDF Pages: 1123-1134 Full Text Reporting Checklist Data Sharing Statement COI Form Open Access

Depletion of insulin-like growth factor 1 receptor increases radiosensitivity in colorectal cancer

Yi Li, Kui Lu, Ben Zhao, Xiaokui Zeng, Shan Xu, Xin Ma, Yunqing Zhi

PDF Pages: 1135-1145 Full Text Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Deaths of colon neuroendocrine tumors are associated with increasing metastatic lymph nodes and lymph node ratio

Changchun Xiao, Baorong Song, Peipei Yi, Yangyang Xie, Biqing Li, Peng Lian, Shaoqing Ding, Yuanming Lu

PDF Pages: 1146-1154 Full Text Reporting Checklist COI Form Open Access

Incidence and detection of high microsatellite instability in colorectal cancer in a Chinese population: a meta-analysis

Congjun Zhang, Hongguang Ding, Shijun Sun, Zhonghua Luan, Guoyan Liu, Zhi Li

PDF Pages: 1155-1163 Full Text Reporting Checklist COI Form Open Access

Colon cancer-associated transcript-1 enhances glucose metabolism and colon cancer cell activity in a high-glucose environment in vitro and in vivo

Ge Cui, Yuxuan Huang, Wenming Feng, Yunliang Yao, Hongchang Zhou, Xining Li, Hui Gong, Jun Liu, Yifan Luo, Yandi Sun, Mengya Zhang, Yan Luo, Ting Zhang

PDF Pages: 1164-1185 Full Text Reporting Checklist Data Sharing Statement COI Form Open Access

CircBACH1/let-7a-5p axis enhances the proliferation and metastasis of colorectal cancer by upregulating CREB5 expression

Jutang Li, Qian Tang, Wei Dong, Yizhou Wang

PDF Pages: 1186-1199 Full Text Reporting Checklist Data Sharing Statement COI Form Open Access

N-myc downstream-regulated gene 2 promotes the protein stability of estrogen receptor beta via inhibition of ubiquitin-protein ligase E3A to suppress colorectal cancer

Jun Zhu, Yongzhi Lv, Jun Hao, Tingyu Shi, Shuai Wang, Ke Wang, Xiaoyan Fan, Yuan Guo, Jian Zhang, Jipeng Li

PDF Pages: 1200-1213 Full Text Reporting Checklist Data Sharing Statement COI Form Open Access

Nomogram model characterized by mutant genes and clinical indexes to identify high-risk patients with stage III/IV colorectal cancer

Kai Liu, Cui Wang, Jiefu Wang, Yang Zhan, Xin Yue, Dalu Kong

PDF Pages: 1214-1223 Full Text Reporting Checklist Data Sharing Statement COI Form Open Access

The inhibitory effects of probiotics on colon cancer cells: in vitro and in vivo studies

Fangjian Shang, Xia Jiang, Haobo Wang, Shihao Chen, Xin Wang, Ying Liu, Shang Guo, Dongyun Li, Weifang Yu, Zengren Zhao, Guiqi Wang

PDF Pages: 1224-1232 Full Text Reporting Checklist Data Sharing Statement COI Form Open Access

The impact of age on prognosis in patients with gastric cancer: experience in a tertiary care centre

Maan El Halabi, Renee Horanieh, Hani Tamim, Deborah Mukherji, Sara Jdiaa, Sally Temraz, Ali Shamseddine, Kassem Barada

PDF Pages: 1233-1241 Full Text Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Crocin reverses 1-methyl-3-nitroso-1-nitroguanidine (MNNG)-induced malignant transformation in GES-1 cells through the Nrf2/Hippo signaling pathway

Zhide Wu, Jianping Hui

PDF Pages: 1242-1252 Full Text Reporting Checklist Data Sharing Statement COI Form Open Access

Correlation between Claudin-18 expression and clinicopathological features and prognosis in patients with gastric cancer

Yufeng Lu, Tielong Wu, Yingyue Sheng, Yuanyuan Dai, Beilei Xia, Yuzheng Xue

PDF Pages: 1253-1260 Full Text Reporting Checklist Data Sharing Statement COI Form Open Access

Short and long-term outcomes after proximal gastrectomy with double tract reconstruction for Siewert type III adenocarcinoma of the esophagogastric junction: a propensity score matching study from a 10-year experience in a high-volume hospital

Fei Ma, Dandan Guo, Bin Zhang, Yonglei Zhang, Liangqun Peng, Qi Ma, Sheqing Ji, Junhui Chai, Yawei Hua, Xiaobing Chen, Hui Wang, Shuning Xu, Suxia Luo

PDF Pages: 1261-1273 Full Text Reporting Checklist Data Sharing Statement COI Form Open Access

Impact of perioperative intravenous lidocaine infusion on postoperative pain and rapid recovery of patients undergoing gastrointestinal tumor surgery: a randomized, double-blind trial

Yue’e Dai, Rong Jiang, Wenjie Su, Man Wang, Yue Liu, Yunxia Zuo

PDF Pages: 1274-1282 Full Text Reporting Checklist Data Sharing Statement COI Form Open Access

A model for predicting post-liver transplantation recurrence in intrahepatic cholangiocarcinoma recipients

Ao Ren, Zhongqiu Li, Xuzhi Zhang, Ronghai Deng, Yi Ma

PDF Pages: 1283-1290 Full Text Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

High expression of the TEFM gene predicts poor prognosis in hepatocellular carcinoma

Zai-Yi Fei, Wei-Si Wang, Su-Fen Li, Jia-Ji Zi, Li Yang, Ting Liu, Song Ao, Qian-Qian Liu, Qing-Hua Cui, Min Yu, Wei Xiong

PDF Pages: 1291-1304 Full Text Reporting Checklist Peer Review File COI Form Open Access

The expression and prognostic value of GLYATL1 and its potential role in hepatocellular carcinoma

Renguo Guan, Weifeng Hong, Jianfeng Huang, Tianyi Peng, Zhen Zhao, Ye Lin, Min Yu, Zhixiang Jian

PDF Pages: 1305-1321 Full Text Reporting Checklist Data Sharing Statement COI Form Open Access

Propofol activates AMPK to inhibit the growth of HepG2 cells in vitro and hepatocarcinogenesis in xenograft mouse tumor models by inducing autophagy

Yixiong Wang, Baozhu Xu, Jianying Zhou, Xianyan Wu

PDF Pages: 1322-1332 Full Text Reporting Checklist Data Sharing Statement COI Form Open Access

Genome-wide association study of the TP53 R249S mutation in hepatocellular carcinoma with aflatoxin B1 exposure and infection with hepatitis B virus

Chuangye Han, Tingdong Yu, Wei Qin, Xiwen Liao, Jianlu Huang, Zhengtao Liu, Long Yu, Xiaoguang Liu, Zhiwei Chen, Chengkun Yang, Xiangkun Wang, Shutian Mo, Guangzhi Zhu, Hao Su, Jiaquan Li, Xue Qin, Ying Gui, Zengnan Mo, Lequn Li, Tao Peng

PDF Pages: 1333-1349 Full Text Reporting Checklist Data Sharing Statement COI Form Open Access

Relationship between plasma cell-free DNA (cfDNA) and prognosis of TACE for primary hepatocellular carcinoma

Kun Ma, Jiayun Liu, Youjin Wang, Yubin Zhong, Zhenfeng Wu, Ruiying Fan, Shanfeng Guo

PDF Pages: 1350-1363 Full Text Reporting Checklist Data Sharing Statement COI Form Open Access

CXCL5/CXCL8 is a promising potential prognostic and tumor microenvironment-related cluster in hepatocellular carcinoma

Jun Zhu, Yifan Zhou, Liang Wang, Jun Hao, Rui Chen, Lei Liu, Jipeng Li

PDF Pages: 1364-1380 Full Text Reporting Checklist COI Form Open Access

Comprehensive analysis of the relationship between competitive endogenous RNA (ceRNA) networks and tumor infiltrating-cells in hepatocellular carcinoma

Jun Zhu, Liang Wang, Yifan Zhou, Jun Hao, Shuai Wang, Lei Liu, Jipeng Li

PDF Pages: 1381-1398 Full Text Reporting Checklist COI Form Open Access

A prospective trial of stereotactic body radiation therapy for unresectable pancreatic cancer testing ablative doses

Stanley L. Liauw, Lisa Ni, Tianming Wu, Fauzia Arif, Denise Cloutier, Mitchell C. Posner, Mark Kozloff, Hedy L. Kindler

PDF Pages: 1399-1407 Full Text Reporting Checklist Data Sharing Statement COI Form Open Access

Chemoradiotherapy for patients with locally advanced or unresectable extra-hepatic biliary cancer

Krishan R. Jethwa, Shilpa Sannapaneni, Trey C. Mullikin, William S. Harmsen, Molly M. Petersen, Phanindra Antharam, Brady Laughlin, Amit Mahipal, Thorvardur R. Halfdanarson, Kenneth W. Merrell, Michelle Neben-Wittich, Terence T. Sio, Michael G. Haddock, Christopher L. Hallemeier

PDF Pages: 1408-1420 Full Text Reporting Checklist Data Sharing Statement COI Form Open Access

A real-world study of the efficacy and safety of anti-programmed cell death-1 therapy combined with chemotherapy or targeted therapy in patients with advanced biliary tract cancer

Danyang Sun, Junxun Ma, Jinliang Wang, Lijie Wang, Sujie Zhang, Guangying Chen, Xiaoyan Li, Pengfei Cui, Xuan Zheng, Yi Hu

PDF Pages: 1421-1430 Full Text Reporting Checklist Data Sharing Statement COI Form Open Access

Highly expressed Claudin18.2 as a potential therapeutic target in advanced gastric signet-ring cell carcinoma (SRCC)

Bo Xu, Fangcen Liu, Qin Liu, Tao Shi, Zhongda Wang, Nandie Wu, Xinyun Xu, Lin Li, Xiangshan Fan, Lixia Yu, Baorui Liu, Jia Wei

PDF Pages: 1431-1439 Full Text Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Review Article

Imaging of pancreatic cancer: An overview

Pavan Tummala, Omer Junaidi, Banke Agarwal

Immunohistochemical features of the gastrointestinal tract tumors

Hannah H. Wong, Peiguo Chu

Techniques of hepatic resection

Robert J. Aragon, Naveenraj L. Solomon

Gastric cancer: Classification, histology and application of molecular pathology

Bing Hu, Nassim El Hajj, Scott Sittler, Nancy Lammert, Robert Barnes, Aurelia Meloni-Ehrig

HDR brachytherapy for anal cancer

Peter Niehoff, Gyoergy Kovács

Colorectal carcinoma: Pathologic aspects

Matthew Fleming, Sreelakshmi Ravula, Sergei F. Tatishchev, Hanlin L. Wang

Original Article

The clinical utility of serum CA 19-9 in the diagnosis, prognosis and management of pancreatic adenocarcinoma: An evidence based appraisal

Umashankar K Ballehaninna, Ronald S Chamberlain

Survival of metastatic gastric cancer: Significance of age, sex and race/ethnicity

Dongyun Yang, Andrew Hendifar, Cosima Lenz, Kayo Togawa, Felicitas Lenz, Georg Lurje, Alexandra Pohl, Thomas Winder, Yan Ning, Susan Groshen, Heinz-Josef Lenz

Review Articles

Assessment of clinical benefit and quality of life in patients undergoing cytoreduction and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for management of peritoneal metastases

Yue Zhu, Nader Hanna, Cherif Boutros, H. Richard Alexander, Jr.

Review Article

Gastric cancer: Classification, histology and application of molecular pathology

Bing Hu, Nassim El Hajj, Scott Sittler, Nancy Lammert, Robert Barnes, Aurelia Meloni-Ehrig

Colorectal carcinoma: Pathologic aspects

Matthew Fleming, Sreelakshmi Ravula, Sergei F. Tatishchev, Hanlin L. Wang

Diet and supplements and their impact on colorectal cancer

Marinos Pericleous, Dalvinder Mandair, Martyn E. Caplin

HIFU for palliative treatment of pancreatic cancer

Tatiana D. Khokhlova, Joo Ha Hwang

Gastrointestinal stromal tumor

Xiaohui Zhao, Changjun Yue

Gastrointestinal lymphomas: Morphology, immunophenotype and molecular features

Marnelli A. Bautista-Quach, Christopher D. Ake, Mingyi Chen, Jun Wang

Imaging of pancreatic cancer: An overview

Pavan Tummala, Omer Junaidi, Banke Agarwal

Preoperative imaging for hepatic resection of colorectal cancer metastasis

Timothy L. Frankel, Richard Kinh Gian Do, William R. Jarnagin

Techniques of hepatic resection

Robert J. Aragon, Naveenraj L. Solomon

Liver-directed therapies in metastatic colorectal cancer

Margaret E. Clark, Richard R. Smith

Imaging preoperatively for pancreatic adenocarcinoma

Jason Alan Pietryga, Desiree E. Morgan

Immunohistochemical features of the gastrointestinal tract tumors

Hannah H. Wong, Peiguo Chu

Current and future systemic treatment options in metastatic pancreatic cancer

Cagatay Arslan, Suayib Yalcin

Radioembolization of hepatic tumors

Andrew Kennedy

FDG PET imaging in the staging and management of gastric cancer

Shane Hopkins, Gary Y Yang

Stereotactic body radiation therapy for liver metastases

Marta Scorsetti, Elena Clerici, Tiziana Comito

The role of epithelial-mesenchymal transition in pancreatic cancer

Jen-Jung Pan, Muh-Hwa Yang

Surgical management of gastric cancer: the East vs. West perspective

Maki Yamamoto, Omar M. Rashid, Joyce Wong

Human papillomavirus tumor infection in esophageal squamous cell carcinoma

Ethan B. Ludmir, Sarah J. Stephens, Manisha Palta, Christopher G. Willett, Brian G. Czito

Molecular pathology of pancreatic neuroendocrine tumors

Mingyi Chen, Michael Van Ness, Yangtong Guo, Jeffrey Gregg

Immunotherapy for advanced gastric and esophageal cancer: preclinical rationale and ongoing clinical investigations

Alexander G. Raufi, Samuel J. Klempner

Original Article

The clinical utility of serum CA 19-9 in the diagnosis, prognosis and management of pancreatic adenocarcinoma: An evidence based appraisal

Umashankar K Ballehaninna, Ronald S Chamberlain

Survival of metastatic gastric cancer: Significance of age, sex and race/ethnicity

Dongyun Yang, Andrew Hendifar, Cosima Lenz, Kayo Togawa, Felicitas Lenz, Georg Lurje, Alexandra Pohl, Thomas Winder, Yan Ning, Susan Groshen, Heinz-Josef Lenz

Insulin caused drug resistance to oxaliplatin in colon cancer cell line HT29

Jiezhong Chen, Xu-Feng Huang, Liang Qiao, Andrew Katsifis

Exosome can prevent RNase from degrading microRNA in feces

Yoshikatsu Koga, Masahiro Yasunaga, Yoshihiro Moriya, Takayuki Akasu, Shin Fujita, Seiichiro Yamamoto, Yasuhiro Matsumura

Multicenter evaluation of the safety and efficacy of radioembolization in patients with unresectable colorectal liver metastases selected as candidates for ⁹⁰Y resin microspheres

Andrew S. Kennedy, David Ball, Steven J. Cohen, Michael Cohn, Douglas M. Coldwell, Alain Drooz, Eduardo Ehrenwald, Samir Kanani, Steven C. Rose, Charles W. Nutting, Fred M. Moeslein, Michael A. Savin, Sabine Schirm, Samuel G. Putnam III, Navesh K. Sharma, Eric A. Wang

Treatment of locally advanced unresectable pancreatic cancer: a 10-year experience

Nadia K Malik, Kilian Salerno May, Rameela Chandrasekhar, Wen Wee Ma, Leayn Flaherty, Renuka Iyer, John Gibbs, Boris Kuvshinoff, Gregory Wilding, Graham Warren, Gary Y Yang

Endoscopic stenting versus operative gastrojejunostomy for malignant gastric outlet obstruction-a systematic review and meta-analysis of randomized and non-randomized trials

Vinayak Nagaraja, Guy D. Eslick, Michael R. Cox

Self-expanding metal stents (SEMS) provide superior outcomes compared to plastic stents for pancreatic cancer patients undergoing neoadjuvant therapy

Megan A. Adams, Michelle A. Anderson, James D. Myles, Shokoufeh Khalatbari, James M. Scheiman

Original Articles

Forthcoming prognostic markers for esophageal cancer: a systematic review and meta-analysis

Vinayak Nagaraja, Guy D. Eslick

Review Articles

Understanding and targeting resistance to anti-angiogenic therapies

Jeffrey M. Clarke, Herbert I. Hurwitz

Markers of resistance to anti-EGFR therapy in colorectal cancer

Walid Shaib, Reena Mahajan, Bassel El-Rayes

Review Article

Alcoholic liver disease- Hepatocellular carcinoma transformation

Samuel W French, James Lee, Jim Zhong, Timothy R Morgan, Virgil Buslon, William Lungo, Barbara A French

Pancreatic adenocarcinoma pathology: changing “landscape”

Lodewijk A. A. Brosens, Wenzel M. Hackeng, G. Johan Offerhaus, Ralph H. Hruban, Laura D. Wood

Refining the management of resectable esophagogastric cancer: FLOT4, CRITICS, OE05, MAGIC-B and the promise of molecular classification

Jeremy Chuang, Jun Gong, Samuel J. Klempner, Yanghee Woo, Joseph Chao

Original Article

Bax expression is a candidate prognostic and predictive marker of colorectal cancer

Venkat R Katkoori, Catalina Suarez-Cuervo, Chandrakumar Shanmugam, Nirag C Jhala, Tom Callens, Ludwine Messiaen, James Posey III, Harvey L Bumpers, Sreelatha Meleth, William E Grizzle, Upender Manne

Survival of metastatic gastric cancer: Significance of age, sex and race/ethnicity

Dongyun Yang, Andrew Hendifar, Cosima Lenz, Kayo Togawa, Felicitas Lenz, Georg Lurje, Alexandra Pohl, Thomas Winder, Yan Ning, Susan Groshen, Heinz-Josef Lenz

The influence of radiation therapy dose escalation on overall survival in unresectable pancreatic adenocarcinoma

William A. Hall, Lauren E. Colbert, Dana Nickleach, Jeffrey Switchenko, Yuan Liu, Theresa Gillespie, Joseph Lipscomb, Claire Hardy, David A. Kooby, Roshan S. Prabhu, John Kauh, Jerome C. Landry

Overall survival analysis of neoadjuvant chemoradiotherapy and esophagectomy for esophageal cancer

Faisal A. Siddiqui, Katelyn M. Atkins, Brian S. Diggs, Charles R. Thomas Jr, John G. Hunter, James P. Dolan

Radiotherapy patterns of care in gastric adenocarcinoma: a single institution experience

Jessica Cheng, Malcolm H. Squires III, John L. Mikell, Sarah B. Fisher, Charles A. Staley III, David A. Kooby, Bassel F. El-Rayes, Walter J. Curran Jr, William A. Hall, Lauren E. Colbert, Joseph W. Shelton, Shishir K. Maithel, Jerome Landry, David S. Yu

Impact of intensity modulated radiation therapy on survival in anal cancer

Jaymin Jhaveri, Lael Rayfield, Yuan Liu, Mudit Chowdhary, Sibo Tian, Richard J. Cassidy, Theresa Gillespie, Pretesh R. Patel, Jerome C. Landry, Kirtesh R. Patel

Immune profiling of microsatellite instability-high and polymerase ε (POLE)-mutated metastatic colorectal tumors identifies predictors of response to anti-PD-1 therapy

Chongkai Wang, Jun Gong, Travis Y. Tu, Peter P. Lee, Marwan Fakih

Palliative care and end-of-life health care utilization in elderly patients with pancreatic cancer

Nizar Bhulani, Arjun Gupta, Ang Gao, Jenny Li, Chad Guenther, Chul Ahn, Elizabeth Paulk, Stephanie Houck, Muhammad S. Beg

Distinctive features of gastrointestinal stromal tumors arising from the colon and rectum

Rebecca Zhu, Fangfang Liu, Gabriella Grisotti, Javier Pérez-Irizarry, Charles H. Cha, Caroline H. Johnson, Daniel J. Boffa, Dale Han, Kimberly L. Johung, Yawei Zhang, Sajid A. Khan

Original Articles

Socioeconomic status, p53 abnormalities, and colorectal cancer

Emily Vogtmann, Chandrakumar Shanmugam, Venkat R. Katkoori, John Waterbor, Upender Manne

Nab-paclitaxel monotherapy in refractory pancreatic adenocarcinoma

Parvin F. Peddi, May Cho, Jian Wang, Feng Gao, Andrea Wang-Gillam

Below are the latest Journal of Gastrointestinal Oncology articles published online ahead of print publication.

Review Article

Gastric cancer: lessons learned from high-incidence geographic regions

Raquel Abengozar, Aayush Sharma, Rohit Sharma

Omics analyses in peritoneal metastasis—utility in the management of peritoneal metastases from colorectal cancer and pseudomyxoma peritonei: a narrative review

Christin Lund-Andersen, Annette Torgunrud, Karianne Giller Fleten, Kjersti Flatmark

A narrative review of intraperitoneal chemotherapy and cytoreductive surgery (CRS) for peritoneal metastases in gastric cancer

Thomas Boerner, Pompiliu Piso

A discussion of the gut microbiome’s development, determinants, and dysbiosis in cancers of the esophagus and stomach

Karan Grover, Stephanie Gregory, John F. Gibbs, Nancy J. Emenaker

Value-based focused global population health management

John F. Gibbs, Ashley Newman, Richard G. Stefanacci

Global trends in pancreas cancer among Asia-Pacific population

Rohit Ranganath, Quyen Chu

State of the art vaccination strategies as primary prevention to reduce incidence of gastrointestinal cancers

Rhea Daniel, Sarah Lowry, Harpreet Pall

Systemic therapy in addition to cytoreduction and hyperthermic intraperitoneal chemotherapy for colorectal peritoneal metastases: recent insights from clinical studies and translational research

Checca Bakkers, Geert A. A. M. Simkens, Ignace H. J. T. De Hingh

Hyperthermic intraperitoneal chemotherapy in prevention of gastric cancer metachronous peritoneal metastases: a systematic review

Mikhail Yu. Reutovich, Olga V. Krasko, Oleg G. Sukonko

Hyperthermic intraperitoneal chemotherapy (HIPEC) for colorectal and appendiceal peritoneal metastases: lessons learned from PRODIGE 7

Peter Cashin, Paul H. Sugarbaker

Neoadjuvant treatment of localized pancreatic adenocarcinoma

Alexis D. Leal, Wells A. Messersmith, Christopher H. Lieu

Narrative review of hyperthermic intraperitoneal chemotherapy (HIPEC) in patients with advanced ovarian cancer: a critical reappraisal of the current evidence

John Spiliotis, Anastasia Prodromidou

Intraperitoneal gemcitabine chemotherapy is safe for patients with resected pancreatic cancer: final clinical and pharmacologic data from a phase II protocol and recommended future directions

Paul H. Sugarbaker, O. Anthony Stuart

Narrative review of cytoreductive surgery and intraperitoneal chemotherapy for peritoneal metastases in ovarian cancer

Thomas Boerner, Oliver Zivanovic, Dennis S. Chi

Review of management and treatment of peritoneal metastases from gastric cancer origin

Israel Manzanedo, Fernando Pereira, Ángel Serrano, Estíbalitz Pérez-Viejo

Intraperitoneal chemotherapy in the treatment of gastric cancer peritoneal metastases: an overview of common therapeutic regimens

Andreas Brandl, Aruna Prabhu

Sequential postoperative intraperitoneal chemotherapy for colorectal cancer with peritoneal metastases: a narrative review

Peter H. Cashin, Wilhelm Graf

Addressing the worldwide hepatocellular carcinoma: epidemiology, prevention and management

Hrishikesh Samant, Hosein Shokouh Amiri, Gazi B. Zibari

The role of oral health in gastrointestinal malignancies

Christian Madsen

Pressurized intraperitoneal aerosol chemotherapy with oxaliplatin (PIPAC-OX) in patients with colorectal peritoneal metastases—a systematic review

Robin J. Lurvink, Koen P. Rovers, Simon W. Nienhuijs, Geert-Jan Creemers, Jacobus W. A. Burger, Ignace H. J. de Hingh

New insights in the pathology of peritoneal surface malignancy

Norman John Carr

Intra-operative hyperthermic intraperitoneal chemotherapy for prevention and treatment of peritoneal metastases from gastric cancer: a narrative review

Zhong-He Ji, Ying Zhang, Yan Li

Value-based chronic care model approach for vulnerable older patients with multiple chronic conditions

John F. Gibbs, Ellen Guarnieri, Quyen D. Chu, Kenneth Murdoch, Arif Asif

Surgery for locally advanced PDAC—is it only about the vessels?

Max Heckler, Thilo Hackert

The brain–gut axis in gastrointestinal cancers

Orna Alpert, Leonid Begun, Tony Issac, Ramon Solhkhah

Implications of the growing incidence of global colorectal cancer

Benjamin W. Vabi, John F. Gibbs, Glenn S. Parker

Can local ablative techniques replace surgery for locally advanced pancreatic cancer?

Ulrike Heger, Thilo Hackert

Esophageal cancer: the rise of adenocarcinoma over squamous cell carcinoma in the Asian belt

Victoria J. Grille, Stuart Campbell, John F. Gibbs, Thomas L. Bauer

Original Article

Asiaticoside inhibits epithelial-mesenchymal transition and stem cell-like properties of pancreatic cancer PANC-1 cells by blocking the activation of p65 and p38MAPK

Yonggang He, Xuehui Peng, Lu Zheng, Yichen Tang, Jing Li, Xiaobing Huang

Surgery with hyperthermic intraperitoneal chemotherapy after response to induction chemotherapy in patients with peritoneal metastasis of gastric cancer

Emel Canbay, Bahar Canbay Torun, Kaan Cosarcan, Cetin Altunal, Bulent Gurbuz, Cagri Bilgic, Canfeza Sezgin, Kerim Kim Kaban, Serpil Yilmaz, Zeliha Yazici

Hyperthermic intra-operative intraperitoneal chemotherapy as an adjuvant to pancreatic cancer resection

Antonios-Apostolos K. Tentes

Octreotide long-acting release (LAR) in combination with other therapies for treatment of neuroendocrine neoplasia: a systematic review

Maria Rinzivillo, Ilaria De Felice, Ludovica Magi, Bruno Annibale, Francesco Panzuto

Safety of perioperative hyperthermic intraperitoneal chemotherapy with gemcitabine in patients with resected pancreatic adenocarcinoma: a pilot study of the clinical trial EudraCT 2016-004298-41

David Padilla-Valverde, Esther García-Santos, Susana Sanchez, Carmen Manzanares, Marta Rodriguez, Lucia González, Alfonso Ambrós, Juana M. Cano, Leticia Serrano, Raquel Bodoque, Teresa Vergara, Jesus Martin

Intraperitoneal paclitaxel: pharmacology, clinical results and future prospects

Paul H. Sugarbaker

CAP2 contributes to tumorigenesis in gastric cancer by targeting transcription factor SOX9

Ying Wan, Shengkui Qiu, Lei Yin, Xuesong Gao, Yasu Jiang, Shichun Feng, Chong Tang

Conversion surgery in patients with pancreatic cancer and peritoneal metastasis

Suguru Yamada, Tsutomu Fujii, Tomohisa Yamamoto, Hideki Takami, Isaku Yoshioka, So Yamaki, Fuminori Sonohara, Kazuto Shibuya, Fuyuhiko Motoi, Satoshi Hirano, Yoshiak Murakami, Hitoshi Inoue, Masamichi Hayashi, Daisuke Hashimoto, Kenta Murotani, Joji Kitayama, Hideki Ishikawa, Yasuhiro Kodera, Mitsugu Sekimoto, Sohei Satoi

Letter to the Editor

Ramucirumab plus FOLFIRI or irinotecan as second-line therapy in advanced or metastatic gastric or gastroesophageal junction adenocarcinoma

Verena Schlintl, Florian Huemer, Richard Greil, Lukas Weiss

Editorial

Global GI malignancies: a population health management perspective

John F. Gibbs, Quyen D. Chu

Case Report

Endoluminal tumor implant of a colorectal cancer in an anal fistula detected by FISH techniques: a case report

Enrique Montero-Mateos, Sofía del Carmen, Julia Sanz, Raquel Rodriguez-García, José Antonio Alcázar, José María Sayagués, Mar Abad

A case of nivolumab-induced cervical lymphadenopathy in a patient with gastric cancer

Koichi Taira, Akie Kimura, Akinobu Nakata, Yuji Nadatani, Shusei Fukunaga, Koji Otani, Shuhei Hosomi, Fumio Tanaka, Noriko Kamata, Yasuaki Nagami, Toshio Watanabe, Yasuhiro Fujiwara

Journal highlight more

Journal of Gastrointestinal Oncology is an open-access, international peer-reviewed journal indexed by PubMed/PubMed Central, Science Citation Index Expanded (SCIE), with a focus on the diagnosis, prevention and clinical investigations of gastrointestinal cancer, including but not limited to, multimodality therapy, markers, imaging and tumor biology.

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In Science Citation Index Expanded (SCIE)

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In PMC

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Journal of Gastrointestinal Oncology is published by AME Publishing Company

The official journal of

Society for Gastrointestinal Oncology (SGO)

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