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New Impact Factor for Journal of Gastrointestinal Oncology: 2.587

We are pleased to announce that the Journal of Gastrointestinal Oncology (JGO) has attained its latest impact factor update for the 2021 citation year: 2.587.

We will strive to follow the best practices in publishing. Here, we would like to extend our heartfelt gratitude to all our Editorial Team Members, Guest Editors, authors, and reviewers for their valuable contributions.

JGO Annual Report (2021)

Greetings from the editorial office of Journal of Gastrointestinal Oncology (JGO).

We are glad to present the 2021 Annual Report of JGO, which has shown the number, internationality, monthly retrieval of JGO in PubMed and pageviews of JGO articles. The newly released 2021 Impact Factor of JGO is 2.892.

We would like to extend our sincere gratitude to our editorial board members, guest editors, reviewers, authors and readers. We wish you a happy, healthy and prosperous 2022 and we look forward to working with you to continue the success of JGO.

Journal of Gastrointestinal Oncology (JGO) is now a member of Committee on Publication Ethics (COPE)

Starting from July 2021, AME Publishing Company is formally recognized a publisher member of Committee on Publication Ethics (COPE) and over 60 AME-published journals become a member of Committee on Publication Ethics (COPE), as part of AME’s commitment to best practice in scholarly publishing. Journal of Gastrointestinal Oncology (JGO) is among the list of COPE membership.

Surgery for Locally Advanced Pancreatic Cancer

In the time of rapidly emerging data on the feasibility of surgery in locally advanced pancreatic cancer (LAPC), this specialized edition of Journal of Gastrointestinal Oncology seeks to summarize and critically evaluate the existing data on the topic and to provide a guidance for best clinical practice for surgical resection and oncologic treatment of LAPC.

Reviewer of the Month (2020-21)

Over the years, many JGO reviewers have made outstanding contributions to the peer review process. They demonstrated professional effort and enthusiasm in their reviews and provided comments that genuinely help the authors to enhance their work.

Hereby, we would like to highlight some of our outstanding reviewers, with a brief interview of their thoughts and insights as a reviewer. Allow us to express our heartfelt gratitude for their tremendous effort and valuable contributions to the scientific process.

Global GI Malignancies

The increasing issues of globalization and caring for our populations have created a unified effort of all healthcare stakeholders worldwide. Population health has emerged to integrate public health, health policy, quality and safety, as well as chronic care management under one roof. Although the concept of population health has been around for generations, a measurable definition of “population-level health outcomes” with the health factors and policy/interventions that influence it was not reported until Kindig and Stoddart in 2003. This focus series of global GI malignancies from a population health management perspective is intended to provide a broad overview of relevant topics.

Current Strategies in Colon Cancer Management

Colorectal cancer is the second most common cancer in females and the third most common in males worldwide. In this issue of Journal of Gastrointestinal Oncology, we will focus on the surgical management of colon cancer and give an update on its latest developments.

Pancreatic Neuroendocrine Tumors

The incidence of pancreatic neuroendocrine tumors (pNETs) continues to increase, prompting renewed interest in the pathophysiology and treatment of this disease. This focused series comprehensively reviews the pathophysiology, tumorigenesis, available clinical trials, and approved therapies for patients with pNETs. A deeper understanding of these factors is necessary to enhance our efforts to improve patient improve patient outcomes through the application of more innovative treatment sequencing.

Implementation of transparent peer review at Journal of Gastrointestinal Oncology (JGO)

Editorial office, Journal of Gastrointestinal Oncology

With a commitment to openness and accountability, and to increase the level of transparency throughout our peer review process, our editorial office has decided to implement a transparent peer review process as an option for all manuscripts submitted to JGO from June 11, 2020.

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Vol 13, No 3 (June, 2022)

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Original Article

Prognosis of patients with esophageal squamous cell carcinoma undergoing surgery versus no surgery after neoadjuvant chemoradiotherapy: a retrospective cohort study

Jiawei Li, Baofu Chen, Xia Wang, Congcong Xu, Dong Chen, Kanghao Zhu, Zixian Jin, Hongbin Qiu, Jianfei Shen, Minhua Ye

PDF Pages: 903-911 Full Text (519) Reporting Checklist Data Sharing Statement COI Form Open Access

Expression of CircATXN7 in esophageal cancer tissues and its effect on cell proliferation and invasion

Delin Liu, Hui Jia, Jianwei Lu, Xi Zou, Ting Qian, Fanyu Peng, Guochun Cao, Min Wang, Shenlin Liu

PDF Pages: 912-922 Full Text (502) Reporting Checklist Data Sharing Statement COI Form Open Access

Predictive effect of J waves on cardiac compression and clinical prognosis of esophageal tumors: a retrospective study

Songcui Shen, Yichen Xie, Pengliang Ju, Wenzhao Li, Jiayuan Zhang, Ruxin Cai, Ruogu Li

PDF Pages: 923-934 Full Text (345) Reporting Checklist Data Sharing Statement COI Form Open Access

Treatment paradigms and survival outcomes in esophageal adenocarcinoma with liver metastasis: a retrospective cohort study using the SEER database

Jing Guo, Chang-Yong Tong, Jian-Guang Shi, Xin-Jian Li

PDF Pages: 935-948 Full Text (454) Reporting Checklist COI Form Open Access

Treatment heterogeneity and overall survival in patients with advanced/metastatic gastric or gastroesophageal junction adenocarcinoma in the United States

Jessica A. Davis, Zhanglin Lin Cui, Madiha Ghias, Xiaohong Li, Robert Goodloe, Chunxiao Wang, Astra M. Liepa, Lisa M. Hess

PDF Pages: 949-957 Full Text (390) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Abrogation of ARF6 in promoting erastin-induced ferroptosis and mitigating capecitabine resistance in gastric cancer cells

Donghua Geng, Huiying Wu

PDF Pages: 958-967 Full Text (612) Reporting Checklist Data Sharing Statement COI Form Open Access

The efficacy and safety of continuous intra-arterial infusion neoadjuvant chemotherapy with surgery for locally advanced gastric cancer: a preliminary pilot study

Bin Li, Rui Tang, Guangqiang Zhang, Jingkai Cheng, Ming Chao, Kefeng Ding

PDF Pages: 968-976 Full Text (415) Reporting Checklist Data Sharing Statement COI Form Open Access

Chemosensitivity of gastric cancer: analysis of key pathogenic transcription factors

Jianze Weng, Aixiang Wu, Jingwen Ying

PDF Pages: 977-984 Full Text (412) Reporting Checklist COI Form Open Access

Resveratrol inhibits the proliferation, invasion, and migration, and induces the apoptosis of human gastric cancer cells through the MALAT1/miR-383-5p/DDIT4 signaling pathway

Zhuying Yang, Liang Xia

PDF Pages: 985-996 Full Text (476) Reporting Checklist Data Sharing Statement COI Form Open Access

Association between preoperative nutritional status, inflammation, and intestinal permeability in elderly patients undergoing gastrectomy: a prospective cohort study

Xining Zhao, Ying Wang, Yuying Yang, Yan Pan, Jie Liu, Shengjin Ge

PDF Pages: 997-1006 Full Text (433) Reporting Checklist Data Sharing Statement COI Form Open Access

Perioperative lymphocyte-to-monocyte ratio changes plus CA199 in predicting the prognosis of patients with gastric cancer

Yueyue Zhu, Wenjing Zhao, Guoxin Mao

PDF Pages: 1007-1021 Full Text (396) Reporting Checklist Data Sharing Statement COI Form Open Access

A retrospective study of clinicopathological characteristics and prognostic factors of Krukenberg tumor with gastric origin

Xiaolin Lin, Ting Han, Meng Zhuo, Tengfei Liu, Zebing Liu, Dongxi Xiang, Hong Li, Xiuying Xiao

PDF Pages: 1022-1034 Full Text (480) Reporting Checklist Data Sharing Statement COI Form Open Access

Decreased expression of claudin-18.2 in alpha-fetoprotein-producing gastric cancer compared to conventional gastric cancer

Weiwei Weng, Meng Zhang, Shujuan Ni, Cong Tan, Midie Xu, Xin Wang, Hui Sun, Lei Wang, Dan Huang, Weiqi Sheng

PDF Pages: 1035-1045 Full Text (426) Reporting Checklist Data Sharing Statement COI Form Open Access

Prognostic value and clinicopathological correlation of the tumor regression grade in neoadjuvant chemotherapy for gastric adenocarcinoma: a retrospective cohort study

Yi Wang, Handong Xu, Can Hu, Pengcheng Yu, Zhehan Bao, Yanqiang Zhang, Ruolan Zhang, Shengjie Zhang, Bing Li, Jean-Marie Aerts, Zhiyuan Xu, Xiangdong Cheng

PDF Pages: 1046-1057 Full Text (431) Reporting Checklist Data Sharing Statement COI Form Open Access

Chromobox 4 (CBX4) promotes tumor progression and stemness via activating CDC20 in gastric cancer

Wen Li, Honghui Chen, Zhenggen Wang, Jingjing Liu, Xinan Lei, Wen Chen

PDF Pages: 1058-1072 Full Text (491) Reporting Checklist Data Sharing Statement COI Form Open Access

Efficacy of hand-assisted laparoscopic surgery (HALS) in older adult patients (≥80 years) with primary colorectal cancer

Takuya Koike, Masaya Mukai, Rin Abe, Yutaro Kamei, Daiki Yokoyama, Shuji Uda, Shigeo Higami, Sayuri Hasegawa, Tomoki Nakamura, Takayuki Tajima, Eiji Nomura, Hiroyasu Makuuchi

PDF Pages: 1073-1080 Full Text (376) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Patterns-of-care disparities among uninsured versus insured patients with anorectal carcinoma referred for radiotherapy at an Urban Safety-Net Hospital

Michael Padgett, Shivam M. Kharod, Catherine E. Mercado, Christopher G. Morris, Michael S. Rutenberg, Romaine C. Nichols Jr

PDF Pages: 1081-1085 Full Text (320) Reporting Checklist Data Sharing Statement COI Form Open Access

The bevacizumab plus oxaliplatin-based chemotherapy regimen is more suitable for metastatic colorectal cancer patients with a history of schistosomiasis: a clinical retrospective analysis

Li-Na Zhou, Chun-Xia Feng, Yan Zhang, Ping Li, Min Tang, Min-Bin Chen, Jun Jin

PDF Pages: 1086-1096 Full Text (353) Reporting Checklist Data Sharing Statement COI Form Open Access

Tripartite motif 52 (TRIM52) promotes proliferation, migration, and regulation of colon cancer cells associated with the NF-κB signaling pathway

Yanjiao Guo, Yiming Zhou, Xiaodong Gu, Jianbin Xiang

PDF Pages: 1097-1111 Full Text (398) Reporting Checklist Data Sharing Statement COI Form Open Access

Efficacy and safety of radiotherapy combined with raltitrexed and irinotecan for treating unresectable recurrent colorectal cancer: a single-arm phase II trial

Xinghui Li, Jinwen Shen, Fan Xia, Ji Zhu

PDF Pages: 1112-1120 Full Text (482) Reporting Checklist Data Sharing Statement COI Form Open Access

Comparison of characteristics between true rectal neuroendocrine tumors and rectal hyperplastic polyps among patients with endoscope-diagnosed rectal neuroendocrine tumors

Yan Weng, Jingxue Ran, Yongmei Peng, Yining Xiang, Liangbi Xu

PDF Pages: 1121-1131 Full Text (327) Reporting Checklist Data Sharing Statement COI Form Open Access

TRIM29 is differentially expressed in colorectal cancers of different primary locations and affects survival by regulating tumor immunity based on retrospective study and bioinformatics analysis

Jing Han, Jing Zuo, Xue Zhang, Long Wang, Dan Li, Yudong Wang, Jiayin Liu, Li Feng

PDF Pages: 1132-1151 Full Text (425) Reporting Checklist Data Sharing Statement COI Form Open Access

c-MYC and HIF1α promoter G-quadruplexes dependent metabolic regulation mechanism of berberine in colon cancer

Lina Wen, Zongqiang Han, Jianhui Li, Yanlin Du

PDF Pages: 1152-1168 Full Text (454) Reporting Checklist Data Sharing Statement COI Form Open Access

Suppression effect and safety of acupuncture on colonic spasm during colonoscopy: a randomized controlled trial

Baoling Chen, Yanyan Ma, Cailing Zhong, Ye Li, Jiahao Mo, Songming Liang, Yao Zhong, Beiping Zhang, Yingxian Li

PDF Pages: 1169-1177 Full Text (380) Reporting Checklist Trial Protocol Data Sharing Statement COI Form Open Access

Expression characteristics of long non-coding RNA in colon adenocarcinoma and its potential value for judging the survival and prognosis of patients: bioinformatics analysis based on The Cancer Genome Atlas database

Ruofan Li, Xu Gao, Haitao Sun, Lixin Sun, Xiaojian Hu

PDF Pages: 1178-1187 Full Text (468) Reporting Checklist COI Form Open Access

Diagnostic genes and immune infiltration analysis of colorectal cancer determined by LASSO and SVM machine learning methods: a bioinformatics analysis

Yan-Rong Li, Ke Meng, Guang Yang, Bao-Hai Liu, Chu-Qiao Li, Jia-Yuan Zhang, Xiao-Mei Zhang

PDF Pages: 1188-1203 Full Text (578) Reporting Checklist COI Form Open Access

Association of social determinants of health with late diagnosis and survival of patients with pancreatic cancer

Jesus C. Fabregas, Kristen E. Riley, Jeannine M. Brant, Thomas J. George, E. John Orav, Miranda B. Lam

PDF Pages: 1204-1214 Full Text (388) Reporting Checklist COI Form Open Access

Clinical efficacy and safety of 3D vascular reconstruction combined with 3D navigation in laparoscopic hepatectomy: systematic review and meta-analysis

Jihua Jiang, Lei Pei, Renya Jiang

PDF Pages: 1215-1223 Full Text (366) Reporting Checklist COI Form Open Access

Diagnostic accuracy of 3D imaging combined with intra-operative ultrasound in the prediction of post-hepatectomy liver failure

Tianchong Wu, Wenhao Huang, Baochun He, Yuehua Guo, Gongzhe Peng, Mingyue Li, Shiyun Bao

PDF Pages: 1224-1236 Full Text (343) Reporting Checklist Data Sharing Statement COI Form Open Access

ZIC5 promotes human hepatocellular carcinoma cell proliferation through upregulating COL1A1

Wenping Song, Weijiang Yu, Ding Li, Cheng Cheng, Xuan Wu, Jinhua Chen, Wenzhou Zhang

PDF Pages: 1237-1247 Full Text (432) Reporting Checklist Data Sharing Statement COI Form Open Access

Study on safety and efficacy of regorafenib combined with transcatheter arterial chemoembolization in the treatment of advanced hepatocellular carcinoma after first-line targeted therapy

Haochen Wang, Weizhong Xiao, Yanjing Han, Shasha Cao, Zhiyuan Zhang, Guang Chen, Yuefeng Hu, Long Jin

PDF Pages: 1248-1254 Full Text (483) Reporting Checklist Data Sharing Statement COI Form Open Access

Knockdown of Obg-like ATPase 1 enhances sorafenib sensitivity by inhibition of GSK-3β/β-catenin signaling in hepatocellular carcinoma cells

Rong Bian, Jinkai Zhao, Zhongcai Yao, Yajun Cai, Chenting Shou, Dayong Lou, Liqin Zhou, Yuanyuan Qian

PDF Pages: 1255-1265 Full Text (471) Reporting Checklist Data Sharing Statement COI Form Open Access

Efficacy and safety of sequential therapy with sorafenib and regorafenib for advanced hepatocellular carcinoma: a two-center study in China

Shao-Hua Ren, Zi-Lin Cui, Meng-Ran Lang, Qiang Li, Wei Zhang, Feng Fang, Qiang Wu, Yun-Long Cui, Hui-Kai Li, Ping Chen, Yamin Zhang, Tianqiang Song

PDF Pages: 1266-1277 Full Text (535) Reporting Checklist Data Sharing Statement COI Form Open Access

Comparison of the safety and prognosis of sequential regorafenib after sorafenib and lenvatinib treatment failure in patients with unresectable hepatocellular carcinoma: a retrospective cohort study

Jian Zhai, Jianwei Liu, Zhigang Fu, Shilei Bai, Xiaowei Li, Zengqiang Qu, Yanfu Sun, Ruiliang Ge, Feng Xue

PDF Pages: 1278-1288 Full Text (509) Reporting Checklist Data Sharing Statement COI Form Open Access

Exploring potential targets of Actinidia Chinensis Planch root against hepatocellular carcinoma based on network pharmacology and molecular docking and development and verification of immune-associated prognosis features for hepatocellular carcinoma

Meilin Qu, Tao Han, Xiaoquan Chen, Qingqing Sun, Qing Li, Mingfang Zhao

PDF Pages: 1289-1307 Full Text (542) Reporting Checklist COI Form Open Access

Correlation analysis of intestinal flora and immune function in patients with primary hepatocellular carcinoma

Simiao Zhang, Lixia Hou, Qingyu Sun

PDF Pages: 1308-1316 Full Text (463) Reporting Checklist Data Sharing Statement COI Form Open Access

IL-1 receptor-associated kinase 1 participates in the modulation of the NLRP3 inflammasome by tumor-associated macrophages in hepatocellular carcinoma

Wei Chen, Mingjuan Hu, Tao Wei, Ying Liu, Tian Tan, Chengfang Zhang, Jiaxuan Weng

PDF Pages: 1317-1329 Full Text (465) Reporting Checklist Data Sharing Statement COI Form Open Access

Antidiabetic treatment improves prognosis after radical resection in hepatocellular carcinoma patients with diabetes mellitus: a retrospective cohort study from 2000 to 2013

Jing-Zhu Cao, Zhen-Guang Wang, Jian Yu, Yuan-Ping Tao, Yuan Yang, Hui Liu, Wei-Ping Zhou, Jin Lu, Qin Huang

PDF Pages: 1330-1339 Full Text (406) Reporting Checklist Data Sharing Statement COI Form Open Access

Prognostic role of myeloid-derived tumor-associated macrophages at the tumor invasive margin in gastric cancer with liver metastasis (GCLM): a single-center retrospective study

Zeyu Wang, Zhongyi Dong, Gang Zhao, Bo Ni, Zi-Zhen Zhang

PDF Pages: 1340-1350 Full Text (439) Reporting Checklist Data Sharing Statement COI Form Open Access

Clinical significance and immunogenomic landscape analysis of glycolysis-associated prognostic model to guide clinical therapy in hepatocellular carcinoma

Qingshan Chen, Leilei Bao, Yueying Huang, Lei Lv, Guoqing Zhang, Yi Chen

PDF Pages: 1351-1366 Full Text (548) Reporting Checklist COI Form Open Access

Efficacy and safety of transcatheter arterial chemoembolization-lenvatinib sequential therapy for patients with unresectable hepatocellular carcinoma: a single-arm clinical study

Ruiqing Chen, Lingbing Li, Ye Li, Ke Song, Chenyu Shen, Pengkai Ma, Zhijun Wang

PDF Pages: 1367-1375 Full Text (565) Reporting Checklist Data Sharing Statement COI Form Open Access

Development of a prognostic score for recommended transarterial chemoembolization candidates with spontaneous rupture of hepatocellular carcinoma

Jixue Zou, Jia Yuan, Hong Chen, Xinghao Zhou, Tongchun Xue, Rongxin Chen, Lan Zhang, Zhenggang Ren

PDF Pages: 1376-1383 Full Text (394) Reporting Checklist Data Sharing Statement COI Form Open Access

Human chorionic gonadotropin-β promotes pancreatic cancer progression via the epithelial mesenchymal transition signaling pathway

Yasunori Uesato, Futoshi Kawamata, Shinichiro Ishino, Shinichiro Ono, Koichi Tamashiro, Hirofumi Koyama, Mitsuhisa Takatsuki

PDF Pages: 1384-1394 Full Text (376) Reporting Checklist Data Sharing Statement COI Form Open Access

Dose-escalated proton therapy with elective nodal irradiation and concomitant chemotherapy for unresectable, borderline resectable, or medically inoperable pancreatic cancer: a phase II trial

Cooper T. Rapp, Michael S. Rutenberg, Christopher G. Morris, Romaine C. Nichols

PDF Pages: 1395-1401 Full Text (377) Reporting Checklist Data Sharing Statement COI Form Open Access

Stereotactic body radiation therapy for the treatment of locally recurrent pancreatic cancer after surgical resection

Abhinav V. Reddy, Colin S. Hill, Shuchi Sehgal, Jin He, Lei Zheng, Joseph M. Herman, Jeffrey Meyer, Amol K. Narang

PDF Pages: 1402-1412 Full Text (419) Reporting Checklist Data Sharing Statement COI Form Open Access

Anatomic patterns of recurrence in biliary tract cancers: does primary tumor site matter?

Andrew J. Sinnamon, Anthony C. Wood, Megan A. Satyadi, Catherine V. Levitt, Olivia Hardy, Mintallah Haider, Richard D. Kim, Daniel A. Anaya, Jason W. Denbo

PDF Pages: 1413-1422 Full Text (386) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Effects of 2-dodecyl-6-methoxycyclohexa-2,5-diene-1,4-dione on autophagy and the PI3K/AKT/mTOR signaling pathway in human cholangiocarcinoma QBC939 cells

Yongfei He, Yanghong Li, Tianyi Liang, Shutian Mo, Yuan Liao, Zijun Chen, Shuqi Zhao, Qingfu Ran, Chuangye Han, Pham Thi Thai Hoa

PDF Pages: 1423-1432 Full Text (465) Reporting Checklist Data Sharing Statement COI Form Open Access

Survival and prognostic factors for postoperative primary appendiceal cancer: a retrospective cohort study based on the Surveillance, Epidemiology, and End Results database

Ying Wang, Yiting Geng, Wenwei Hu

PDF Pages: 1433-1443 Full Text (407) Reporting Checklist COI Form Open Access

UBE2C promotes the progression of pancreatic cancer and glycolytic activity via EGFR stabilization-mediated PI3K-Akt pathway activation

Jing-Zhu Cao, Gang Nie, Hao Hu, Xiao Zhang, Chen-Ming Ni, Zhi-Ping Huang, Guang-Lei Qiao, Liu Ouyang

PDF Pages: 1444-1453 Full Text (412) Reporting Checklist Data Sharing Statement COI Form Open Access

Review Article

Comparison of neoadjuvant regimens for resectable gastroesophageal junction cancer: a systematic review of randomized clinical trials across three decades

Go Nishikawa, Pratyusha Banik, Rajat Thawani, Adel Kardosh, Stephanie G. Wood, Nima Nabavizadeh, Emerson Y. Chen

PDF Pages: 1454-1466 Full Text (441) Reporting Checklist Peer Review File COI Form Open Access

Case Report

Unexpected plasmablastic lymphoma in a young adult with unknown HIV infection: case report

Austin L. Gray, Daniel Ding, Ziphezinhle Ncube, Kaushik Mukherjee, Justin Kerstetter, Yan Liu, Jun Wang

PDF Pages: 1467-1472 Full Text (391) Reporting Checklist COI Form Open Access

Immunotherapy in synchronous MSI-H rectal adenocarcinoma and upper tract urothelial carcinoma: a case report

Jacqueline Hsieh-Wong, James Liu, Jasmine Huynh, Mamta Parikh, Edward Kim, Jun Gong, Wissam Halabi, Mamatha Siricilla, Anupam Mitra, Kyra Toomey, May Cho

PDF Pages: 1473-1480 Full Text (651) Reporting Checklist COI Form Open Access

Jejunojejunal intussusception with chronic bleeding caused by gastrointestinal stromal tumor: a case report and literature review

Hao Li, Hongchang Ren, Hongwei Sun, Lina Song, Yan Wang, Jianwu Yang, Peiming Sun, Yan Cui

PDF Pages: 1481-1488 Full Text (364) Reporting Checklist COI Form Open Access

A case report of malignant neuroectodermal tumor of the gastrointestinal tract without common gene fusion in a soft tissue tumor

Zi-Lin Liu, Bin Zhou, Yi-Jun Zhao, Miao-Qing Yu, Jie Liang, Yong Li

PDF Pages: 1489-1498 Full Text (379) Reporting Checklist COI Form Open Access

Colorectal leiomyosarcoma with BRCA2 mutation benefit from treatment with olaparib: a case report

Lei Hong, Ya-Nan Wang, Xue Zhang, Xinliang Zhou, Shaoshuang Fan, Mian Xu, Shanshan Zhang, Da Jiang

PDF Pages: 1499-1504 Full Text (439) Reporting Checklist COI Form Open Access

Fourth-line rescue treatment ripretinib of advanced small intestine gastrointestinal stromal tumors who achieved partial response: a case report

Bo Liu, Youwei Kou

PDF Pages: 1505-1513 Full Text (473) Reporting Checklist COI Form Open Access

Letter to the Editor

Does contrast-enhanced intraoperative ultrasound improve the sensitivity and predictive value of colorectal cancer liver metastasis detection?

Yuxia Guo, Xiangjin Zhu, Zehao Hu, Anli Zhao, Jiangfeng Wu

PDF Pages: 1514-1515 Full Text (327) COI Form Open Access

Original Article

The clinical utility of serum CA 19-9 in the diagnosis, prognosis and management of pancreatic adenocarcinoma: An evidence based appraisal

Umashankar K Ballehaninna, Ronald S Chamberlain

Survival of metastatic gastric cancer: Significance of age, sex and race/ethnicity

Dongyun Yang, Andrew Hendifar, Cosima Lenz, Kayo Togawa, Felicitas Lenz, Georg Lurje, Alexandra Pohl, Thomas Winder, Yan Ning, Susan Groshen, Heinz-Josef Lenz

Review Article

Imaging of pancreatic cancer: An overview

Pavan Tummala, Omer Junaidi, Banke Agarwal

Immunohistochemical features of the gastrointestinal tract tumors

Hannah H. Wong, Peiguo Chu

Techniques of hepatic resection

Robert J. Aragon, Naveenraj L. Solomon

Gastric cancer: Classification, histology and application of molecular pathology

Bing Hu, Nassim El Hajj, Scott Sittler, Nancy Lammert, Robert Barnes, Aurelia Meloni-Ehrig

HDR brachytherapy for anal cancer

Peter Niehoff, Gyoergy Kovács

Colorectal carcinoma: Pathologic aspects

Matthew Fleming, Sreelakshmi Ravula, Sergei F. Tatishchev, Hanlin L. Wang

Review Articles

Assessment of clinical benefit and quality of life in patients undergoing cytoreduction and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for management of peritoneal metastases

Yue Zhu, Nader Hanna, Cherif Boutros, H. Richard Alexander, Jr.

Original Article

The clinical utility of serum CA 19-9 in the diagnosis, prognosis and management of pancreatic adenocarcinoma: An evidence based appraisal

Umashankar K Ballehaninna, Ronald S Chamberlain

Survival of metastatic gastric cancer: Significance of age, sex and race/ethnicity

Dongyun Yang, Andrew Hendifar, Cosima Lenz, Kayo Togawa, Felicitas Lenz, Georg Lurje, Alexandra Pohl, Thomas Winder, Yan Ning, Susan Groshen, Heinz-Josef Lenz

Insulin caused drug resistance to oxaliplatin in colon cancer cell line HT29

Jiezhong Chen, Xu-Feng Huang, Liang Qiao, Andrew Katsifis

Exosome can prevent RNase from degrading microRNA in feces

Yoshikatsu Koga, Masahiro Yasunaga, Yoshihiro Moriya, Takayuki Akasu, Shin Fujita, Seiichiro Yamamoto, Yasuhiro Matsumura

Multicenter evaluation of the safety and efficacy of radioembolization in patients with unresectable colorectal liver metastases selected as candidates for ⁹⁰Y resin microspheres

Andrew S. Kennedy, David Ball, Steven J. Cohen, Michael Cohn, Douglas M. Coldwell, Alain Drooz, Eduardo Ehrenwald, Samir Kanani, Steven C. Rose, Charles W. Nutting, Fred M. Moeslein, Michael A. Savin, Sabine Schirm, Samuel G. Putnam III, Navesh K. Sharma, Eric A. Wang

Treatment of locally advanced unresectable pancreatic cancer: a 10-year experience

Nadia K Malik, Kilian Salerno May, Rameela Chandrasekhar, Wen Wee Ma, Leayn Flaherty, Renuka Iyer, John Gibbs, Boris Kuvshinoff, Gregory Wilding, Graham Warren, Gary Y Yang

Endoscopic stenting versus operative gastrojejunostomy for malignant gastric outlet obstruction-a systematic review and meta-analysis of randomized and non-randomized trials

Vinayak Nagaraja, Guy D. Eslick, Michael R. Cox

Self-expanding metal stents (SEMS) provide superior outcomes compared to plastic stents for pancreatic cancer patients undergoing neoadjuvant therapy

Megan A. Adams, Michelle A. Anderson, James D. Myles, Shokoufeh Khalatbari, James M. Scheiman

Review Article

Gastric cancer: Classification, histology and application of molecular pathology

Bing Hu, Nassim El Hajj, Scott Sittler, Nancy Lammert, Robert Barnes, Aurelia Meloni-Ehrig

Colorectal carcinoma: Pathologic aspects

Matthew Fleming, Sreelakshmi Ravula, Sergei F. Tatishchev, Hanlin L. Wang

Diet and supplements and their impact on colorectal cancer

Marinos Pericleous, Dalvinder Mandair, Martyn E. Caplin

HIFU for palliative treatment of pancreatic cancer

Tatiana D. Khokhlova, Joo Ha Hwang

Gastrointestinal stromal tumor

Xiaohui Zhao, Changjun Yue

Gastrointestinal lymphomas: Morphology, immunophenotype and molecular features

Marnelli A. Bautista-Quach, Christopher D. Ake, Mingyi Chen, Jun Wang

Imaging of pancreatic cancer: An overview

Pavan Tummala, Omer Junaidi, Banke Agarwal

Preoperative imaging for hepatic resection of colorectal cancer metastasis

Timothy L. Frankel, Richard Kinh Gian Do, William R. Jarnagin

Techniques of hepatic resection

Robert J. Aragon, Naveenraj L. Solomon

Liver-directed therapies in metastatic colorectal cancer

Margaret E. Clark, Richard R. Smith

Imaging preoperatively for pancreatic adenocarcinoma

Jason Alan Pietryga, Desiree E. Morgan

Immunohistochemical features of the gastrointestinal tract tumors

Hannah H. Wong, Peiguo Chu

Current and future systemic treatment options in metastatic pancreatic cancer

Cagatay Arslan, Suayib Yalcin

Radioembolization of hepatic tumors

Andrew Kennedy

FDG PET imaging in the staging and management of gastric cancer

Shane Hopkins, Gary Y Yang

Stereotactic body radiation therapy for liver metastases

Marta Scorsetti, Elena Clerici, Tiziana Comito

The role of epithelial-mesenchymal transition in pancreatic cancer

Jen-Jung Pan, Muh-Hwa Yang

Surgical management of gastric cancer: the East vs. West perspective

Maki Yamamoto, Omar M. Rashid, Joyce Wong

Human papillomavirus tumor infection in esophageal squamous cell carcinoma

Ethan B. Ludmir, Sarah J. Stephens, Manisha Palta, Christopher G. Willett, Brian G. Czito

Molecular pathology of pancreatic neuroendocrine tumors

Mingyi Chen, Michael Van Ness, Yangtong Guo, Jeffrey Gregg

Immunotherapy for advanced gastric and esophageal cancer: preclinical rationale and ongoing clinical investigations

Alexander G. Raufi, Samuel J. Klempner

Original Articles

Forthcoming prognostic markers for esophageal cancer: a systematic review and meta-analysis

Vinayak Nagaraja, Guy D. Eslick

Review Articles

Understanding and targeting resistance to anti-angiogenic therapies

Jeffrey M. Clarke, Herbert I. Hurwitz

Markers of resistance to anti-EGFR therapy in colorectal cancer

Walid Shaib, Reena Mahajan, Bassel El-Rayes

Original Article

Bax expression is a candidate prognostic and predictive marker of colorectal cancer

Venkat R Katkoori, Catalina Suarez-Cuervo, Chandrakumar Shanmugam, Nirag C Jhala, Tom Callens, Ludwine Messiaen, James Posey III, Harvey L Bumpers, Sreelatha Meleth, William E Grizzle, Upender Manne

Survival of metastatic gastric cancer: Significance of age, sex and race/ethnicity

Dongyun Yang, Andrew Hendifar, Cosima Lenz, Kayo Togawa, Felicitas Lenz, Georg Lurje, Alexandra Pohl, Thomas Winder, Yan Ning, Susan Groshen, Heinz-Josef Lenz

The influence of radiation therapy dose escalation on overall survival in unresectable pancreatic adenocarcinoma

William A. Hall, Lauren E. Colbert, Dana Nickleach, Jeffrey Switchenko, Yuan Liu, Theresa Gillespie, Joseph Lipscomb, Claire Hardy, David A. Kooby, Roshan S. Prabhu, John Kauh, Jerome C. Landry

Overall survival analysis of neoadjuvant chemoradiotherapy and esophagectomy for esophageal cancer

Faisal A. Siddiqui, Katelyn M. Atkins, Brian S. Diggs, Charles R. Thomas Jr, John G. Hunter, James P. Dolan

Radiotherapy patterns of care in gastric adenocarcinoma: a single institution experience

Jessica Cheng, Malcolm H. Squires III, John L. Mikell, Sarah B. Fisher, Charles A. Staley III, David A. Kooby, Bassel F. El-Rayes, Walter J. Curran Jr, William A. Hall, Lauren E. Colbert, Joseph W. Shelton, Shishir K. Maithel, Jerome Landry, David S. Yu

Impact of intensity modulated radiation therapy on survival in anal cancer

Jaymin Jhaveri, Lael Rayfield, Yuan Liu, Mudit Chowdhary, Sibo Tian, Richard J. Cassidy, Theresa Gillespie, Pretesh R. Patel, Jerome C. Landry, Kirtesh R. Patel

Immune profiling of microsatellite instability-high and polymerase ε (POLE)-mutated metastatic colorectal tumors identifies predictors of response to anti-PD-1 therapy

Chongkai Wang, Jun Gong, Travis Y. Tu, Peter P. Lee, Marwan Fakih

Palliative care and end-of-life health care utilization in elderly patients with pancreatic cancer

Nizar Bhulani, Arjun Gupta, Ang Gao, Jenny Li, Chad Guenther, Chul Ahn, Elizabeth Paulk, Stephanie Houck, Muhammad S. Beg

Distinctive features of gastrointestinal stromal tumors arising from the colon and rectum

Rebecca Zhu, Fangfang Liu, Gabriella Grisotti, Javier Pérez-Irizarry, Charles H. Cha, Caroline H. Johnson, Daniel J. Boffa, Dale Han, Kimberly L. Johung, Yawei Zhang, Sajid A. Khan

Review Article

Alcoholic liver disease- Hepatocellular carcinoma transformation

Samuel W French, James Lee, Jim Zhong, Timothy R Morgan, Virgil Buslon, William Lungo, Barbara A French

Pancreatic adenocarcinoma pathology: changing “landscape”

Lodewijk A. A. Brosens, Wenzel M. Hackeng, G. Johan Offerhaus, Ralph H. Hruban, Laura D. Wood

Refining the management of resectable esophagogastric cancer: FLOT4, CRITICS, OE05, MAGIC-B and the promise of molecular classification

Jeremy Chuang, Jun Gong, Samuel J. Klempner, Yanghee Woo, Joseph Chao

Original Articles

Socioeconomic status, p53 abnormalities, and colorectal cancer

Emily Vogtmann, Chandrakumar Shanmugam, Venkat R. Katkoori, John Waterbor, Upender Manne

Nab-paclitaxel monotherapy in refractory pancreatic adenocarcinoma

Parvin F. Peddi, May Cho, Jian Wang, Feng Gao, Andrea Wang-Gillam

Below are the latest Journal of Gastrointestinal Oncology articles published online ahead of print publication.

Original Article

Lymph node metastases rate of locoregional and non-locoregional lymph node stations in gastric cancer

Mees Hendrik Siert de Jong, Suzanne Sarah Gisbertz, Mark Ivo van Berge Henegouwen, Werner Adriaan Draaisma

Survival comparison of stage IIA rectal cancer with or without neoadjuvant therapy: a SEER database analysis with propensity score matching

Han Yan, Peng-Yuan Wang, Ying-Chao Wu, Yu-Cun Liu

Surgical treatment and survival analysis of primary duodenal malignant tumor: a retrospective cohort study

Zhicheng Zhao, Jiehong Zhang, Chuan Li, Tong Liu, Weidong Li

Clinicopathological prognostic factors for gallbladder carcinoma: a retrospective study

Fátima Ramalhosa, Maria João Amaral, Marco Serôdio, Rui Caetano Oliveira, Paulo Teixeira, Maria Augusta Cipriano, José Guilherme Tralhão

A phase II trial of gemcitabine and erlotinib followed by ChemoProton therapy plus capecitabine and oxaliplatin for locally advanced pancreatic cancer

Samrat M. Sanghvi, Alex R. Coffman, Chung-Tsen Hsueh, Joseph Kang, Annie Park, Naveenraj L. Solomon, Carlos A. Garberoglio, Mark E. Reeves, Jerry D. Slater, Gary Y. Yang

Characterization of somatic mutations and pathway alterations during hepatocellular carcinoma vascular invasion using next- generation sequencing

Qi Li, Qifan Zhang, Jinzhang Chen, Mengya Zang, Xiaoyun Hu, Rong Li, Jinlin Hou, Jie Zhou

Validation of a genotype-based algorithm that identifies individuals with low, intermediate, and high serum CA19-9 levels in cancer- free individuals and in patients with colorectal cancer

Andreas Wannhoff, Simone Werner, Sha Tao, Hermann Brenner, Daniel N. Gotthardt

Association between progression-free survival and metal stent patency in patients with advanced pancreatic cancer

Jinwoo Ahn, Dong-Won Ahn, Jaewoo Park, Kwangrok Jung, Jong-Chan Lee, Jin-Hyeok Hwang, Ji Bong Jeong, Jaihwan Kim

Bioinformatics analysis of the prognostic and immunotherapeutic significance of NPRL2 in stomach adenocarcinoma

Yilin Pi, Yuning Zhan, Jitao Song, Xin Jin, Jing Chen

The role of tumor-infiltrating B cells in the tumor microenvironment of hepatocellular carcinoma and its prognostic value: a bioinformatics analysis

Jixue Zou, Chubin Luo, Haoyang Xin, Tongchun Xue, Xiaoying Xie, Rongxin Chen, Lan Zhang

Systematic review and meta-analysis of endoscopic ultrasonography in staging diagnosis of esophageal cancer after neoadjuvant radiotherapy and chemotherapy

Xiaodong Li, Yixiao Wang, Min Kong, Jiang Lin

Lymphadenectomy with venation is preferred compared to skeletonization for patients with rectal and sigmoid colon cancer: a retrospective cohort study

Wei Ge, Hai-Yan Gong, Li-Hua Shao, Gang Chen, Yu-Dong Qiu

Role of local therapy in the management of patients with metastatic anal squamous cell carcinoma: a National Cancer Database study

Rami P. Atallah, Yining Zhang, Katerina Zakka, Renjian Jiang, Zhonglu Huang, Walid L. Shaib, Maria Diab, Mehmet Akce, Christina Wu, Bassel F. El-Rayes, Olatunji B. Alese

High levels of triglycerides, apolipoprotein B, and the number of colorectal polyps are risk factors for colorectal polyp recurrence after endoscopic resection: a retrospective study

Jia-Yu Du, Gui-Ying Huang, Yong-Chun Xie, Nan-Xi Li, Zhi-Wei Lin, Li Zhang

Luteolin suppresses the growth of colon cancer cells by inhibiting the IL-6/STAT3 signaling pathway

Jingwen Jiang, Fengting Zhu, Hui Zhang, Tao Sun, Fangfang Fu, Xuewu Chen, Yanhong Zhang

Glypican 1 promotes proliferation and migration in esophagogastric adenocarcinoma via activating AKT/GSK/β-catenin pathway

Akshay Pratap, Anqi Li, Lindsey Westbrook, Anna K. Gergen, Sanchayita Mitra, Argudit Chauhan, Linling Cheng, Michael J. Weyant, Martin McCarter, Sachin Wani, Robert Alexander Meguid, John D. Mitchell, Mitchell Cohen, David Fullerton, Xianzhong Meng

A post-marketing safety study of ramucirumab with FOLFIRI in patients with metastatic colorectal cancer

Toshiki Masuishi, Soshi Nagaoka, Long Jin, Kenichi Yoshizawa

Intratumoral CD8⁺ T cells as a potential positive predictor of chemoimmunotherapy response in PD-L1-negative advanced gastric cancer patients: a retrospective cohort study

Gangling Tong, Meiqin Zhu, Yaoxu Chen, Shubo Wang, Boran Cheng, Shubin Wang, Wangjun Liao

Construction and validation of a novel prognostic model using the cellular senescence-associated long non-coding RNA in gastric cancer: a biological analysis

Guoqing Wang, Zhilei Mao, Xiao Zhou, Yiming Zou, Min Zhao

Low CPEB1 levels may predict the benefit of 5-fluorouracil treatment in patients with colon or stomach adenocarcinoma

Jing-Zhu Cao, Dan-Dan Niu, Zhi-Ping Huang, Yong-Gang Hong, Zhen-Guang Wang, Le Yang, Bo-Lun Zhao, Guang-Lei Qiao, Liu Ouyang

Development of a novel combined nomogram model integrating Rad-score, age and ECOG to predict the survival of patients with hepatocellular carcinoma treated by transcatheter arterial chemoembolization

Aiai Liu, Bo Liu, Xiaodong Duan, Bo Yang, Yiren Wang, Ping Dong, Ping Zhou

Study on efficacy and safety of transcatheter arterial chemoembolization (TACE) combined with regorafenib and PD-1 antibody versus continued TACE combined with regorafenib in patients with hepatocellular carcinoma after failed second-line treatment with regorafenib

Haochen Wang, Weizhong Xiao, Yanjing Han, Shasha Cao, Zhiyuan Zhang, Guang Chen, Yuefeng Hu, Long Jin

The efficacy and safety of gemcitabine-based combination therapy vs. gemcitabine alone for the treatment of advanced pancreatic cancer: a systematic review and meta-analysis

Zhaohuan Zhang, Shuling He, Ping Wang, Yibing Zhou

Analysis of safety and efficacy of laparoscopic radical gastrectomy combined with or without indocyanine green tracer fluorescence technique in treatment of gastric cancer: a retrospective cohort study

Xiaoning Chen, Zhengwei Zhang, Feng Zhang, Xuanchen Tao, Xu Zhang, Zeyu Sun, Shibo Sun

Bioinformatics analysis of immune infiltrates and tripartite motif (TRIM) family genes in hepatocellular carcinoma

Jun Cao, Bingbing Su, Rui Peng, Hao Tang, Daoyuan Tu, Yuhong Tang, Jie Zhou, Guoqing Jiang, Shengjie Jin, Qian Wang, Aoqing Wang, Renjie Liu, Qiangwei Deng, Chi Zhang, Dousheng Bai

Review Article

Let food be thy medicine: the role of diet in colorectal cancer: a narrative review

Ying Zheng, Lingnan Meng, Hao Liu, Lijuan Sun, Yongzhan Nie, Qiong Wu, Daiming Fan, Mengbin Li

Research progress on microRNAs as molecular markers in pancreatic cancer: a narrative review

Rui-Biao Fu, Xi Chen, Yan Chen, Qing-Huang Ye, Bin Yang, Qian Shao, Jin-Hui Zhu

The evolving treatment paradigm of locally advanced rectal cancer: a narrative review

Muhammad Awawda, Tarek Taha, Saeed Salman, Salem Billan, Adham Hijab

A narrative review of the evolving role of immunotherapy in the management of esophageal and gastric cancer

Ankit Madan, Hope E. Uronis, John H. Strickler

Letter to the Editor

Was ulcerative colitis one of the risk factors of colorectal cancer?

Qiaoqiao Guo, Qiaoyang Xu, Xiangjin Zhu, Yinghong Guo, Jiangfeng Wu

Is D2 laparoscopic gastrectomy essential for elderly patients with advanced gastric cancer?

Qingbo Feng, Tao Zhang, Ming Xie

Case Report

Proteogenomic analysis in an early onset diffuse gastric cancer patient revealed alterations in PIK3R1, TP53, SMAD4 and a potential role of the PI3K-AKT and EGFR pathways: a case report

Miguel Cordova-Delgado, Mauricio P. Pinto, Gonzalo Pizarro, Elard Koch, Cristian Vargas, Mauricio Hernández, Guillermo Nourdin, Pablo Saldivia, Maria Paz Rodriguez Z., Alejandro Berkovits, Patricio Manque, Juvenal A. Rios, Benjamin Garcia-Bloj, Marcelo Garrido

Journal highlight more

Journal of Gastrointestinal Oncology is an open-access, international peer-reviewed journal indexed by PubMed/PubMed Central, Science Citation Index Expanded (SCIE), with a focus on the diagnosis, prevention and clinical investigations of gastrointestinal cancer, including but not limited to, multimodality therapy, markers, imaging and tumor biology.