Vol 12, No 6 (December 31, 2021) - Journal of Gastrointestinal Oncology

Original Article

Clinical outcomes of first line FOLFIRINOX vs. gemcitabine plus nab-paclitaxel in metastatic pancreatic cancer at the Yale Smilow Hospital System

Timil Patel, Joseph Miccio, Michael Cecchini, Thejal Srikumar, Stacey Stein, Jeremy Kortmanksy, Kimberly Johung, Jill Lacy

PDF Pages: 2547-2556 Full Text (2252) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Outcomes of patients with borderline resectable and resectable pancreatic adenocarcinoma treated with neoadjuvant three-week course chemoradiotherapy using capecitabine-based versus gemcitabine-based concurrent chemotherapy

Shane S. Neibart, Swati Mamidanna, Anupama Chundury, Mutlay Sayan, H. Richard Alexander, David A. August, Lyudmyla D. Berim, Patrick M. Boland, Miral S. Grandhi, Prateek Gulhati, Howard S. Hochster, Russell C. Langan, Kristen R. Spencer, Timothy J. Kennedy, Matthew P. Deek, Salma K. Jabbour

PDF Pages: 2557-2566 Full Text (1438) Reporting Checklist Data Sharing Statement COI Form Open Access

Social determinants of health associated with poor outcome for rural patients following resected pancreatic cancer

Quyen D. Chu, Mei-Chin Hsieh, John F. Gibbs, Xiao-Cheng Wu

PDF Pages: 2567-2578 Full Text (1522) Reporting Checklist Peer Review File COI Form Open Access

Treatment at a high-volume academic research program mitigates racial disparities in pancreatic adenocarcinoma

Quyen D. Chu, Mei-Chin Hsieh, John F. Gibbs, Xiao-Cheng Wu

PDF Pages: 2579-2590 Full Text (923) Reporting Checklist Peer Review File COI Form Open Access

Safety and efficacy of combination chemotherapy regimens in older adults with pancreatic ductal adenocarcinoma: a systematic review

Patricia Saade-Lemus, Leah Biller, Andrea Bullock

PDF Pages: 2591-2599 Full Text (988) Reporting Checklist Peer Review File COI Form Open Access

Comprehensive analysis of prognostic value and immune infiltration of calpains in pancreatic cancer

Chuan Lan, Haoyou Tang, Sheng Liu, Lin Ma, Jianshui Li, Xi Wang, Yifu Hou

PDF Pages: 2600-2621 Full Text (1471) Reporting Checklist COI Form Open Access

LINC00857 promotes the proliferation of pancreatic cancer via MET, STAT3, and CREB

Ye Song, Yingying Liang, Qingfeng Zou, Shaoting Zeng, Hanhong Lin, Meiyuan Liu, Xiaoyan Liu, Jike Du, Guoan Chen, Lei Zou, Wenmei Su, Feiyu Niu

PDF Pages: 2622-2630 Full Text (1282) Reporting Checklist Data Sharing Statement COI Form Open Access

Specific genomic alterations and prognostic analysis of perihilar cholangiocarcinoma and distal cholangiocarcinoma

Yuanwen Zheng, Yejun Qin, Wei Gong, Hongguang Li, Bin Li, Yu Wang, Baoting Chao, Shulei Zhao, Luguang Liu, Shuzhan Yao, Junping Shi, Xiaoliang Shi, Kai Wang, Shifeng Xu

PDF Pages: 2631-2642 Full Text (2641) Reporting Checklist Data Sharing Statement COI Form Open Access

Utility of tumor-informed circulating tumor DNA in the clinical management of gastrointestinal malignancies

Shannon Zhang, Danielle Brazel, Priyanka Kumar, Liudmila N. Schafer, Benjamin Eidenschink, Maheswari Senthil, Farshid Dayyani

PDF Pages: 2643-2652 Full Text (1677) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Bioinformatics analysis identifying FBXO45 gene as a potential oncogene in esophageal cancer

Jian Zhang, Yiping Zhou, Bo Zhang, Chunguo Wang, Baofu Chen, Haitao Ma

PDF Pages: 2653-2664 Full Text (1314) Reporting Checklist COI Form Open Access

A randomized trial of negative pressure wound therapy technology combined with intermittent instillation in the treatment of neck anastomotic leakage after esophageal cancer surgery

Bao-Jia Luo, Hui-Qin Zhang, Jiu-Di Zhong, Xiang-Zi He, Fang Shen, Mei-Chun Zheng, Yong-Shan Wen, Jin-Bo Li, Ming-Zhu Xin

PDF Pages: 2665-2674 Full Text (1053) Reporting Checklist Trial Protocol Data Sharing Statement COI Form Open Access

Peripheral blood inflammation indices are effective predictors of anastomotic leakage in elective esophageal surgery

Cai-Xia Wu, Ding-Yu Rao, Cheng-Peng Sang, Shen-Yu Zhu, Liang Gu, Yan-Yang Wu, Jian-Feng Wang, Hua-Qiu Shi, Xiang-Cai Wang, Zhi-Xian Tang

PDF Pages: 2675-2684 Full Text (883) Reporting Checklist Data Sharing Statement COI Form Open Access

Impact of postoperative lymph node status on the prognosis of esophageal squamous cell carcinoma after esophagectomy following neoadjuvant chemoradiotherapy: a retrospective study

Zhiyong Sun, Xin Xu, Xiaojing Zhao, Xiumei Ma, Qing Ye

PDF Pages: 2685-2695 Full Text (1048) Reporting Checklist Data Sharing Statement COI Form Open Access

PD-L1 immunohistochemistry comparison of 22C3 and 28-8 assays for gastric cancer

Yukiya Narita, Eiichi Sasaki, Toshiki Masuishi, Hiroya Taniguchi, Shigenori Kadowaki, Seiji Ito, Yasushi Yatabe, Kei Muro

PDF Pages: 2696-2705 Full Text (3017) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

A novel robust nomogram based on preoperative hemoglobin and albumin levels and lymphocyte and platelet counts (HALP) for predicting lymph node metastasis of gastric cancer

Xu Wang, Qijin He, Huixi Liang, Jiani Liu, Xin Xu, Kui Jiang, Jie Zhang

PDF Pages: 2706-2718 Full Text (1235) Reporting Checklist Data Sharing Statement COI Form Open Access

Microsatellite instability in Chinese gastric cancer and its correlation with clinical characteristics

Xinyu Li, Lan Zhang, Chunxiao Wang, Junli Huang, Jinfeng Zhu, Yisen Huang, Yifeng Chen, Jing Jia, Guozhong Jiang

PDF Pages: 2719-2727 Full Text (1386) Reporting Checklist Data Sharing Statement COI Form Open Access

LncRNA POT1-AS1 accelerates the progression of gastric cancer by serving as a competing endogenous RNA of microRNA-497-5p to increase PDK3 expression

Wei-Min Chen, Yi-Ming Chen, Si-Yuan Jiang, Yuan-Ping Tao, Yong-Gang Hong, Le Yang, Hao Zheng, Jian-Qing Chen

PDF Pages: 2728-2742 Full Text (1471) Reporting Checklist Data Sharing Statement COI Form Open Access

Open distal gastrectomy versus laparoscopic distal gastrectomy for early gastric cancer: a retrospective study

Feng Wang, Shengbo Zhang, Wei Zhao, Deyou Wang, Sifeng Tang, Qiwen Zhang

PDF Pages: 2743-2748 Full Text (784) Reporting Checklist Data Sharing Statement COI Form Open Access

Identification of a 3-gene signature for predicting the prognosis of stage II colon cancer based on microsatellite status

Xiangxiong Huang, Heyang Xu, Yujie Zeng, Qiusheng Lan, Lu Liu, Wei Lai, Zhonghua Chu

PDF Pages: 2749-2762 Full Text (1130) Reporting Checklist COI Form Open Access

Prognosis of rectal neuroendocrine tumors after endoscopic resection: a single-center retrospective study

Yue Zheng, Kehang Guo, Ruijie Zeng, Zhendao Chen, Wanwei Liu, Xiaoguang Zhang, Weimin Liang, Jianhua Liu, Hao Chen, Weihong Sha

PDF Pages: 2763-2774 Full Text (1567) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Tumor mutation burden determined by a 645-cancer gene panel and compared with microsatellite instability and mismatch repair genes in colorectal cancer

Zhaofei Zhou, Kang Li, Qiang Wei, Lingxiang Chen, You Shuai, Yajing Wang, Kang He, Lixiang Si, Yuejiao Zhong, Jianwei Lu

PDF Pages: 2775-2787 Full Text (1679) Reporting Checklist Data Sharing Statement COI Form Open Access

Identification and validation of xenobiotic metabolism-associated prognostic signature based on five genes to evaluate immune microenvironment in colon cancer

Lina Wen, Zongqiang Han

PDF Pages: 2788-2802 Full Text (1388) Reporting Checklist COI Form Open Access

LncRNA-CASC7 inhibits the proliferation and migration of colon cancer by negatively regulating the PI3K/Akt signaling pathway

Bo Hao, Hexin Wen, Yingying Sun, Zhenghong Le, Zongbing Zhang, Mulin Liu, Ting Hu

PDF Pages: 2803-2813 Full Text (1135) Reporting Checklist Data Sharing Statement COI Form Open Access

Correlation of ulcerative colitis and colorectal cancer: a systematic review and meta-analysis

Yansong Wang, Pu Wang, Lixiang Shao

PDF Pages: 2814-2822 Full Text (1408) Reporting Checklist COI Form Open Access

Analysis of dynamic molecular networks: the progression from colorectal adenoma to cancer

Yuchen Jiang, Feifeng Song, Xiaoping Hu, Dandan Guo, Yujia Liu, Jiafeng Wang, Liehao Jiang, Ping Huang, Yiwen Zhang

PDF Pages: 2823-2837 Full Text (1393) Reporting Checklist COI Form Open Access

Combined detection of preoperative neutrophil to lymphocyte ratio and interleukin-6 as an independent prognostic factor for patients with non-metastatic colorectal cancer

Zhifeng Yang, Yongjing Li, Ke Zhang, Xuejie Deng, Shaoqi Yang, Zhen Wang

PDF Pages: 2838-2845 Full Text (1298) Reporting Checklist Data Sharing Statement COI Form Open Access

Dynamics of neutrophil-to-lymphocyte ratio predict outcomes of metastatic colorectal carcinoma patients treated by FOLFOX

Qian Liu, Yanfeng Xi, Guangzhao He, Xiaoqian Li, Feng Zhan

PDF Pages: 2846-2853 Full Text (1101) Reporting Checklist Data Sharing Statement COI Form Open Access

Identification of methyltransferase-like protein 11B as a new prognostic biomarker for colorectal cancer through an analysis of The Cancer Genome Atlas

Yun Zhou, Yan Zhang, Renhong Guo, Chenchen Li, Ning Sun

PDF Pages: 2854-2871 Full Text (1111) Reporting Checklist Data Sharing Statement COI Form Open Access

High expression of MAGE-C1 gene in colorectal cancer is associated with its poor prognosis

Yu Tian, Ping Liang, Lihua Zhang, Xiufen Zhang, Xiaoli Wang, Yufen Jin, Xiaowei Qi, Yankui Liu

PDF Pages: 2872-2881 Full Text (1308) Reporting Checklist Data Sharing Statement COI Form Open Access

Secondary colon cancer in patients with ulcerative colitis: a systematic review and meta-analysis

Li Zhang, Huatian Gan

PDF Pages: 2882-2890 Full Text (1457) Reporting Checklist COI Form Open Access

A three-phase trans-ethnic study reveals B7-H3 expression is a significant and independent biomarker associated with colon cancer overall survival

Yuan Gao, Yu Xu, Meiqin Gao, Aimin Huang, Pan Chi

PDF Pages: 2891-2905 Full Text (1297) Reporting Checklist Data Sharing Statement COI Form Open Access

Pattern of distant metastases and predictive nomograms in colorectal mucinous adenocarcinoma: a SEER analysis

Lian Lian, Xue-Fei Xu, Xiao-Ming Shen, Tie-Ao Huang, Xian-Min Li, Shu-Guang Han, Chong Zhou, You-You Xia

PDF Pages: 2906-2918 Full Text (1720) Reporting Checklist COI Form Open Access

A systematic review and meta-analysis on the efficacy of Compound Kushen Injection in 3 kinds of digestive tract tumor

Wuguang Zhang, Wenqian Gong, Xiansong He, Changhai Wu, Xiaolong Tu

PDF Pages: 2919-2929 Full Text (1191) Reporting Checklist COI Form Open Access

Prediction of late recurrence after radiofrequency ablation of HBV-related hepatocellular carcinoma with the age-male-albumin-bilirubin-platelets (aMAP) risk score: a multicenter study

Yujing Xin, Xinyuan Zhang, Yi Yang, Yi Chen, Yanan Wang, Xiang Zhou, Xiao Li

PDF Pages: 2930-2942 Full Text (1286) Reporting Checklist Data Sharing Statement COI Form Open Access

Second-line treatment with nivolumab, cabozantinib, regorafenib, or best supportive care in patients with advanced hepatocellular carcinoma: analysis at a Hispanic-majority NCI-designated cancer center

Jeffrey Xia, Jonathan Gelfond, Sukeshi Patel Arora

PDF Pages: 2943-2951 Full Text (1454) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

The treatment choices and outcome of hepatocellular carcinoma in hemophilic patients with human immunodeficiency virus/ hepatitis C virus (HIV/HCV) coinfection due to contaminated blood products in Japan

Mitsuhisa Takatsuki, Koji Natsuda, Masaaki Hidaka, Koji Sawada, Motohiro Shindo, Tomoyuki Endo, Takeshi Hagiwara, Hiroshi Yotsuyanagi, Tomohiko Koibuchi, Kunihisa Tsukada, Haruka Uemura, Kazuhiko Hayashi, Tomoko Uehira, Eiji Mita, Masahiro Yamamoto, Soichiro Takahama, Susumu Eguchi

PDF Pages: 2952-2959 Full Text (891) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

Surgical microwave ablation for multifocal non-resectable liver metastases: a single institution experience treating five or more liver lesions

Jillian K. Wothe, Kendall R. McEachron, Schelomo Marmor, Jacob S. Ankeny, Christopher J. LaRocca, Benjamin Spilseth, Robben Schat, Eric H. Jensen

PDF Pages: 2960-2965 Full Text (1061) Reporting Checklist Data Sharing Statement Peer Review File COI Form Open Access

High expression of Ran binding protein 1 predicts poor outcomes in hepatocellular carcinoma patients: a Cancer Genome Atlas database analysis

Zhengxiao Wei, Xiaoqiong Duan, Qi Li, Qingfeng Li, Yu Wang

PDF Pages: 2966-2984 Full Text (1322) Reporting Checklist COI Form Open Access

Screening of a novel autophagy-related prognostic signature and therapeutic targets in hepatocellular carcinoma

Wei Chen, Ming-Juan Hu, Xiao-Lan Zhong, Lin-Hua Ji, Jian Wang, Cheng-Fang Zhang, Rui Zhang, Hao-Ming Lin

PDF Pages: 2985-2998 Full Text (1755) Reporting Checklist COI Form Open Access

Effects of recombinant human adenovirus type 5 combined with transarterial chemoembolization on postoperative metastasis and recurrence of hepatocellular carcinoma patients

Ke Wu, Nan You, Lu Zheng

PDF Pages: 2999-3007 Full Text (1174) Reporting Checklist Data Sharing Statement COI Form Open Access

The effect of PPP2CA expression on the prognosis of patients with hepatocellular carcinoma and its molecular biological characteristics

Jingchang Liang, Yu Huang, Chenglei Yang, Shen Huang, Jinlong Xie, Xiang Nong, Jianyong Liu, Yumei Zhang, Zhiming Zhang

PDF Pages: 3008-3021 Full Text (1846) Reporting Checklist Data Sharing Statement COI Form Open Access

Short-term efficacy of precise hepatectomy and traditional hepatectomy for primary liver cancer: a systematic review and meta-analysis

Xu Niu, Jing Liu, Zhangdong Feng, Teng Zhang, Tuo Su, Wei Han

PDF Pages: 3022-3032 Full Text (1011) Reporting Checklist COI Form Open Access

Long noncoding RNA NEAT1 changes exosome secretion and microRNA expression carried by exosomes in hepatocellular carcinoma cells

Shengning Zhang, Yuanyi Mang, Li Li, Jianghua Ran, Yingpeng Zhao, Laibang Li, Yang Gao, Wang Li, Guoyu Chen, Jun Ma

PDF Pages: 3033-3049 Full Text (1444) Reporting Checklist Data Sharing Statement COI Form Open Access

Significance of circulating tumor cells in the portal vein regarding metastases and vascular invasion in hepatocellular carcinoma patients

Xiaojuan Zhao, Jingge Zhao, Lianyuan Tao, Yujin Pan, Long Yang, Xijun Zhang, Jianjun Yuan, Haohui Zhu

PDF Pages: 3050-3060 Full Text (1262) Reporting Checklist Data Sharing Statement COI Form Open Access

Prognostic prediction and gene regulation network of EIF2S2 in hepatocellular carcinoma based on data mining

Piyou Ji, Haitao Wang, Yu Cheng, Shaohua Liang

PDF Pages: 3061-3078 Full Text (1572) Reporting Checklist COI Form Open Access

ANTXR1 as a potential prognostic biomarker for hepatitis B virus-related hepatocellular carcinoma identified by a weighted gene correlation network analysis

Tao Si, Xuejian Ning, Haihui Chen, Zhengguo Hu, Linglu Dun, Na Zheng, Ping Huang, Liu Yang, Ping Yi

PDF Pages: 3079-3092 Full Text (1880) Reporting Checklist COI Form Open Access

REXO4 acts as a biomarker and promotes hepatocellular carcinoma progression

Yun Ruan, Weipeng Chen, Cheng Gao, Yingying Xu, Min Shi, Zhuyi Zhou, Guoxiong Zhou

PDF Pages: 3093-3106 Full Text (1449) Reporting Checklist Data Sharing Statement COI Form Open Access

iMDT Corner

Application of low anterior mediastinal tracheostomy for locally advanced cervicothoracic esophageal cancer undergoing total laryngopharyngoesophagectomy: a case report

Chunji Chen, Raja Flores, Biniam Kidane, Masatsugu Hamaji, Xufeng Guo

PDF Pages: 3107-3114 Full Text (1172) Reporting Checklist COI Form Open Access

Review Article

Pathobiology, irradiation dosimetric parameters and therapy of radiation-induced gastric damage: a narrative review

Michael J. McKay, Richard Foster

PDF Pages: 3115-3122 Full Text (1291) Reporting Checklist COI Form Open Access

Educational Case Series of the Memorial Sloan Kettering Cancer Center

Hepatoid esophagogastric adenocarcinoma and tumoral heterogeneity: a case report

Tiago Biachi de Castria, Laura Tang, Marcello Moro Queiroz, Beatriz Mendes Awni, Viktoriya Paroder, Ali Shamseddine, Giovanni Mendonca Bariani, Deborah Mukherji, Charbel F. Matar, Gustavo dos Santos Fernandes, Ashwaq El-Olayan, Fouad Sabatin, Rawad Elias, Ranju Gupta, Yelena Y. Janjigian, Ghassan K. Abou-Alfa

PDF Pages: 3123-3132 Full Text (1728) Reporting Checklist Peer Review File COI Form Open Access

Case Report

Durable clinical benefit from PARP inhibition in a platinum-sensitive, BRCA2-mutated pancreatic cancer patient after earlier progression on placebo treatment on the POLO trial: a case report

Douglas Rubinson, Brian M. Wolpin, Ilana S. Warsofsky, David P. Ryan, Kimberly Perez, Osama Rahma, Harshabad Singh, Matthew B. Yurgelun, Geoffrey I. Shapiro, Andrew J. Aguirre, Alan D. D’Andrea, James M. Cleary

PDF Pages: 3133-3140 Full Text (2513) Reporting Checklist Peer Review File COI Form Open Access