%0 Journal Article %T Percutaneous biliary drainage catheter insertion in patients with extensive hepatic metastatic tumor burden %A Langman, Eun L. %A Suhocki, Paul V. %A Hurwitz, Herbert I. %A Morse, Michael A. %A Burbridge, Rebecca A. %A Smith, Tony P. %A Kim, Charles Y. %J Journal of Gastrointestinal Oncology %D 2016 %B 2016 %9 %! Percutaneous biliary drainage catheter insertion in patients with extensive hepatic metastatic tumor burden %K %X Background: Patients with metastatic disease of the liver can have hyperbilirubinemia due to a number of reasons, including biliary obstruction. The purpose of this study was to analyze patient outcomes after percutaneous biliary drainage (PBD) catheter insertion in patients with extensive hepatic metastatic tumor burden. Methods: Out of 746 PBD insertions, 44 patients (24 males, 20 females, mean age 57.4 years, range, 34–80 years) had metastatic malignancy with a hepatic tumor burden of greater than 20% parenchymal volume based on pre-procedure computed tomography (CT) or magnetic resonance imaging (MRI). Laboratory data before and after PBD insertion were compared. Survival and outcomes analysis performed. A subanalysis was performed on patients with CT-demonstrated catheter traversal of tumoral tissue. Results: A PBD catheter was successfully inserted in all patients. The mean serum bilirubin level decreased significantly from 10.9±6.4 mg/dL immediately prior to PBD insertion to 7.1±5.6 mg/dL (P Conclusions: In patients with hyperbilirubinemia and extensive hepatic metastatic disease burden, survival was dismal after PBD catheter insertion. Serum bilirubin level normalization occurred rarely. %U https://jgo.amegroups.org/article/view/8516 %V 7 %N 6 %P 875-881 %@ 2219-679X