TY - JOUR AU - Arslan, Cagatay AU - Yalcin, Suayib PY - 2014 TI - Current and future systemic treatment options in metastatic pancreatic cancer JF - Journal of Gastrointestinal Oncology; Vol 5, No 4 (August 22, 2014): Journal of Gastrointestinal Oncology Y2 - 2014 KW - N2 - Although pancreatic adenocarcinoma is the fourth leading cause of cancer death, only modest improvement has been observed in the past two decades, single agent gemcitabine has been the only standard treatment in patients with advanced disease. Recently newer agents such as nab-paclitaxel, nimotuzumab and regimens such as FOLFIRINOX have been shown to have promising activity being superior to gemcitabine as a single agent. With better understanding of tumour biology coupled with the improvements in targeted and immunotherapies, there is increasing expectation for better response rates and extended survival in pancreatic cancer. UR - https://jgo.amegroups.org/article/view/2782