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Estimation of hepatocellular carcinoma mortality using aspartate aminotransferase to platelet ratio index

   
@article{JGO25308,
	author = {Kelvin Allenson and David Roife and Lillian S. Kao and Tien C. Ko and Curtis J. Wray},
	title = {Estimation of hepatocellular carcinoma mortality using aspartate aminotransferase to platelet ratio index},
	journal = {Journal of Gastrointestinal Oncology},
	volume = {11},
	number = {2},
	year = {2018},
	keywords = {},
	abstract = {Background: Hepatocellular carcinoma (HCC) patients with cirrhosis are high-risk for invasive procedures. Identification of those at risk may prevent complications and allow more informed decision-making. The aspartate aminotransferase (AST) to platelet ratio index (APRI) is a measure of cirrhosis that we hypothesize predicts survival and may estimate HCC mortality.
Methods: Institutional retrospective study of all HCC patients. Demographics and labs [bilirubin, international normalized ratio (INR), creatinine, AST and platelets] were recorded at the date-of-diagnosis to calculate APRI and the Model for End-Stage Liver Disease score (MELD). Poor survival was defined as death within 30-days from diagnosis. Models were created to determine predictors of death within 30-days and overall survival. 
Results: A total of 829 patients comprised this study and },
	issn = {2219-679X},	url = {https://jgo.amegroups.org/article/view/25308}
}