TY - JOUR AU - Le Baut, Guillaume AU - Guilloit, Jean-Marc AU - Leprince, Vincent AU - Ollivier, Yann AU - Dubos-Arvis, Catherine AU - Do, Pascal AU - Sutter, Jasmine AU - Loge, Ludovic AU - Gervais, Radj PY - 2018 TI - Oxaliplatin-induced bronchiolitis obliterans organizing pneumonia following hyperthermic intraperitoneal chemotherapy JF - Journal of Gastrointestinal Oncology; Vol 9, No 3 (June 01, 2018): Journal of Gastrointestinal Oncology Y2 - 2018 KW - N2 - Oxaliplatin given systemically is associated with pneumonitis in less than 1% of cases. This case report describes acute respiratory failure, due to bronchiolitis organising pneumonia, in a patient with colorectal carcinoma being treated with hyperthermic intraperitoneal chemotherapy which included oxaliplatin and CPT-11 (irinotecan). The clinical course, the lack of an identifiable infectious agent and the complete response to corticosteroids suggested a drug-induced cause. After ruling out CPT-11, oxaliplatin was considered to be the causal agent. The unusual feature of this case was that pneumonitis developed after intraperitoneal administration of oxaliplatin. Oxaliplatin-associated respiratory complications can occur whatever route the drug is administered. UR - https://jgo.amegroups.org/article/view/18306