Article Abstract

A case of periampullary adenocarcinoma in neurofibromatosis type 1

Authors: C. Andrew Kistler, Jennifer M. Johnson, Jordan M. Winter, Jeffrey P. Baliff, Ali A. Siddiqui, Ashwin R. Sama


Neurofibromatosis type 1 (NF-1) is an autosomal dominant genetic disorder with a known predisposition to gastrointestinal neoplasms such as stromal tumors and carcinoids. Adenocarcinomas (ACs) of the gastrointestinal tract are relatively rare in patients with NF-1, especially those found in the periampullary region. We present a case report of periampullary adenocarcinoma in a 56-year-old woman with NF-1 who presented with abdominal pain and obstructive jaundice.