Article Abstract

Anal condylomas: predictors of recurrence and progression to high-grade dysplasia/carcinoma in situ

Authors: Armando Peixoto, Marco Silva, Rui Castro, Rosa Coelho, Alexandre Sarmento, Guilherme Macedo


Condyloma acuminatum is caused by human papilloma virus (HPV) infection. Individuals with condylomata acuminata are at an increased risk for anogenital cancers, mainly anal condylomas with dysplasia are precursors of anal squamous cell carcinoma. There are over 70 distinct HPV subtypes; approximately 35 types are specific for the anogenital epithelium and have varying potentials to cause malignant change, such as cervical or anal cancer (1).